Pfizer

Senior Associate Scientist, Oncology Medicinal Chemistry

Employer
Pfizer
Location
La Jolla, California
Salary
Competitive
Posted
November 25 2021
Ref
4829630
Position Type
Full Time
Organization Type
Pharma
Job Type
Staff Scientist
ROLE SUMMARY

We are seeking a highly motivated synthetic chemist who will contribute to the Oncology Medicinal Chemistry Department located in La Jolla, CA. As part of this group, the successful applicant will contribute through innovative synthetic chemistry tothedeliveryof clinical candidates aligned with the Oncology Research portfolio.

ROLE RESPONSIBILITIES
  • Develop, troubleshoot and optimize synthetic routes, including modular routes for rapid analog generation and efficient scalable routes for preclinical candidates, based on discussions with supervisor and team members
  • Employ enabled routes to synthesize medicinal chemistry targets in singleton or parallel format
  • Build effective partnerships with outsourcing points of contact, analytical, technology, pharmaceutical sciences and process chemistry groups, to efficiently execute synthetic deliverables
  • Actively participate in discussions and present results in chemistry team meetings
  • Adhere to all safety, scientific record keeping, and compliance requirements


BASIC QUALIFICATIONS
  • Master's degree in synthetic organic chemistry or Bachelor's degree with at least 2 years industrial experience as a synthetic organic chemist
  • Solid knowledge of synthetic organic chemistry reaction mechanisms and reactivity
  • Experience as a synthetic organic chemist familiar with a range of reaction types and having demonstrated multi-step synthesis, purification and characterization of organic compounds, especially using NMR and mass spectroscopy
  • Ability to effectively communicate (oral and written) with supervisor and project team members


PREFERRED QUALIFICATIONS
  • Experience in methodology development and familiarity in either organometallic chemistry, catalysis, peptide chemistry or chemical biology
  • Experience in retrosynthetic analysis and capable of designing synthetic routes that efficiently meet project needs
  • Demonstrated independence in the laboratory and in problem solving through careful experiment design, data analysis, and mechanistic insight


Please submit your resume and optional cover letter and 1-2 page research summary

ADDITIONAL JOB INFORMATION:
  • Eligible for employee referral bonus


Pfizer requires all U.S. new hires to be fully vaccinated for COVID-19 prior to the first date of employment. As required by applicable law, Pfizer will consider requests for Reasonable Accommodations.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development

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