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Research Associate

Spark Therapeutics
Philadelphia, Pennsylvania
Salary not provided
Closing date
Feb 23, 2022

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Health Sciences, Drug Development
Job Type
Research Scientist
Organization Type
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Job Details

The Research Associate will normally receive instructions on routine work and instructions on new assignments and may provide guidance to more junior team members.

The Research Associate will participate in molecular assay development and analysis of samples to support multiple preclinical studies for advancing gene therapy programs across all therapeutic areas. S/he will assess bio distribution and transgene under the guidance and supervision of senior scientists and manager.

The primary duties include:

1. Sample preparation and extraction of DNA and RNA using manual and automated methods.

2. Assist qPCR assay development and run qPCR analysis following established SOP.

3. Present in lab meetings and attend cross-team meetings, assist in project tracking and management.

4. Follow company policies, training programs, quality system and developing good lab skills.

5. General lab work such as lab maintenance, operation related tasks assigned by supervisor.


Assist in qPCR assay development and analysis of samples

Sample preparation and extraction of DNA and RNA

General lab tasks assigned by supervisor

Education and Experience Requirements

BA/BS in biological sciences preferred. Generally, has 0-3 years of relevant experience

Key Skills, Abilities, and Competencies

Good learning skills including following instructions, paying attention to details and good documentation are essential.

1. Knowledge implementing and troubleshooting experiments

2. Ability to critically analyze problems, develop potential solutions and evaluate impact to the research organization

3. Ability to assume independent ownership of protocols and experiments

4. Advanced technical lab skills

Complexity and Problem Solving

Refer to established procedures and policies

Worked is performed under general direction

Participates in determining objectives of assignment

Plan schedules and arranges own activities in accomplishing objectives

Work is reviewed upon completion for adequacy in meeting objectives

Good understanding and application of principles, concepts, practices, standards

Please be aware that Spark mandates COVID-19 vaccination of all employees regardless of work location. Accommodations may be made in accordance with applicable law.

Nearest Major Market: Philadelphia

Join the Spark Team

We were born of innovation, springing from the curiosity, imagination and dedication of remarkable scientists and healthcare visionaries. Our shared mission is to challenge the inevitability of genetic disease by discovering, developing, and delivering treatments in ways unimaginable - until now.

We don't follow footsteps. We create the path.


At Spark Therapeutics, a fully integrated, commercial company committed to discovering, developing and delivering gene therapies, we challenge the inevitability of genetic diseases, including blindness, hemophilia, lysosomal storage disorders and neurodegenerative diseases.

Founded in March 2013 as a result of the technology and know-how accumulated over two decades at Children’s Hospital of Philadelphia (CHOP), our investigational therapies have the potential to provide long-lasting effects, dramatically and positively changing the lives of patients with conditions where no, or only palliative, therapies exist. Greater understanding of the human genome and genetic abnormalities have allowed our scientists to tailor investigational therapies to patients suffering from very specific genetic diseases. This approach holds great promise in developing effective treatments to a host of inherited diseases. Our initial focus is on treating orphan diseases.

Headquartered in dynamic Philadelphia, we are a diverse, experienced team united in our goal to break down barriers for people and families affected by genetic diseases. As our name suggests, our investigational, one-time therapies are designed to spark healthy biology, and deliver potentially life-altering transformation for people and families affected by genetic disease. Spark is a member of the Roche Group.

Find Us
3737 Market Street
Suite 1300
United States
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