GSK

Investigator, Cancer Biology (Oncology)

Employer
GSK
Location
Cambridge, MA
Salary
Competitive
Posted
November 09 2021
Ref
312683
Organization Type
Pharma
Site Name: Cambridge 300 Technology Square Posted Date: Nov 9 2021 We are seeking a highly motivated, enthusiastic, skilled in vitro cancer biologists within the GSK Oncology Synthetic Lethality Research Unit located in Cambridge, MA. The successful candidate will work together with cross-functional teams to discover and develop novel oncology drugs with a clear genetic relationship to cancer. The primary responsibilities of this position will be to design, develop and interpret in vitro cancer biology assays to enable studies from novel target validation through clinical candidate nomination. Expertise in high-content imaging assay development and analysis is required and a strong proficiency in cancer biology is greatly preferred. Why You? Basic Qualifications: PhD in Cell Biology, Molecular Biology, Biochemistry, Pharmacology, or related life sciences field and 3 or more years of post-graduate research experience or non-PhD with at least 10 years of pharmaceutical drug discovery experience. Two or more years experience in Cancer Biology Two or more years practical expertise with high content imaging assay development and software for data analysis. Preferred Qualifications Deep knowledge in DNA damage response (DDR), DNA damage repair pathways and oncogenic driver pathways. Experience in independent design and execution of high-content cell-based imaging assays to define functional response, mechanism of action and biomarkers for oncology small molecules. Demonstrated experience in cell biology and hands-on experience with cell-based assay development. Experience with the development and characterization of disease-relevant cellular systems utilizing molecular biology, function genomics (siRNA, CRISPR) and small molecule perturbation. Demonstrated ability to work effectively in a team/matrix environment Excellent written and verbal communication skills with a strong background in cancer biology reflected in peer reviewed publications Why GSK? Our values and expectations are at the heart of everything we do and form an important part of our culture. These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities: Operating at pace and agile decision-making - using evidence and applying judgement to balance pace, rigour and risk. Committed to delivering high quality results, overcoming challenges, focusing on what matters, execution. Continuously looking for opportunities to learn, build skills and share learning. Sustaining energy and well-being *LI-GSK. If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US). GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class. At GSK, the health and safety of our employees are of paramount importance. As a science-led healthcare company on a mission to get ahead of disease together, we believe that supporting vaccination against COVID-19 is the single best thing we can do in the US to ensure the health and safety of our employees, complementary workers, workplaces, customers, consumers, communities, and the patients we serve. GSK has made the decision to require all US employees to be fully vaccinated against COVID-19, where allowed by state or local law and where vaccine supply is readily available. The only exceptions to this requirement are employees who are approved for an accommodation for religious, medical or disability-related reasons. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site. Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit GSK's Transparency Reporting For the Record site.

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