Research Scientist

Location
Houston, Texas
Salary
Competitive
Posted
November 11 2021
Ref
145096
Discipline
Health Sciences
Organization Type
Healthcare/Hospital
Key Functions

  1. The Research scientist will be knowleagable on the biology of cancer metastasis. The successful candidate must have a strong background in microscopy and/or preclinical mouse models for cancer and be able to design novel projects, create hypothesis driven experiments, maintain excellent descriptions of experiments performed, standardize and validate new methods and be able to interpret results, including computational image analysis and statistical procedures.
  2. The Research Scientist will investigate the mechanisms underlying the mechanical stress response during invasion and metastasis, as well as development of novel interventions to prevent both metastasis and reduce the cancer cells' ability to survive the stresses encountered during the metastatic journey.
  3. The candidate will become familiar with appropriate pre-clinical and clinical melanoma, liver and prostate cancer models (transgenic mice, cell lines and PDXs), will plan and conduct experiments on the molecular and immunologic properties of cancer microenvironment and its relationship to cancer cell evolution. These tasks will require strong organizational skills, innovative thinking, diligent execution of experimental procedures and interpretation skills, as well as the ability to perform independent troubleshooting on assays.
  4. The Research Scientist will use intravital multiphoton microscopy and 3D multiplexed analysis of tissues; develop and apply models of hematogenous metastasis; 3D in vitro invasion analysis in organotypic tissue culture; preclinical intravital microscopy models of systemic metastasis
  5. This person will particularly need research and interpersonal skills to work with basic research scientists, trainees including urology/medical oncology fellows, as well as clinicians for patient-based sample acquisition, processing, and analyses as a part of very dynamic translational research team.
  6. The candidate will work closely with lab PI for assistance in grant preparation, manuscript writing, assist with the report of experimental results for presentation in scientific meetings and publication in peer-reviewed journals.
  7. Conducts critical experimental record keeping in laboratory notebooks. Performs routine data analysis and reporting. All conducted projects require review literature, experimental design, alternative approaches, organization, time-line, coordination, data interpretation, future directions and compiles, writes and submits report to supervisor.
  8. Participate in laboratory meetings to present research findings to colleagues. Attend to academic conferences or meetings for oral or visual production of posters.
  9. Supervises, mentors, and counsels trainees and other laboratory personnel with respect to proper laboratory techniques, the use of laboratory equipment and safety procedures. Guide, teach and supervise technicians and students to accomplish research or other laboratory duties.
  10. Write manuscripts, research proposals and apply for grant funding, and collaborate with lab members to reinforce expertise and speed up research programs.
  11. Other duties as assigned.

PhD in one of the natural sciences or related field or Medical degree With PhD, no experience required. With Medical degree, two years of experience in experimental or scientific work. It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law. http://www.mdanderson.org/about-us/legal-and-policy/legal-statements/eeo-affirmative-action.html

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