Non-Clinical Research, In Vivo Research Associate (CNS)

Employer
Spark Therapeutics
Location
Pipersville, Pennsylvania
Salary
Salary not provided
Closing date
Jan 25, 2022

View more

Job Details

The In Vivo Research Associate will be responsible for performing In Vivo studies to support all CNS therapeutic areas and other therapeutic areas of the Non-Clinical department, if needed.

Additional responsibilities include but are not limited to:

  • Oversee and perform large numbers of in vivo studies concurrently and according to the experimental designs.
  • Perform ICV/Intrathecal/Intraparenchymal/IV/IP/SC injections in mice and rats, monitor animal health, collect blood samples, collect CSF perform necropsies.
  • Perform behavioral studies, brain surgeries as required.
  • Maintain mouse breeding colonies.
  • Ensure accurate data recording.
  • General supplies and reagent inventory and ordering.
  • Interact with CNS team scientists and provide constant feedback.
  • Work crossfunctionally with liver and ocular teams and provide support to other R&D In Vivo needs.

Perform In Vivo experiments and animal monitoring according to applicable regulations in support of the CNS team and other therapeutic areas.

Maintain accurate record of procedures and provide results/comments to study directors

Education and Experience Requirements

  • Bachelor’s degree in relevant field and 3 years hands on experience with rodents required or equivalent experience is acceptable. Master’s degree preferred.
  • Generally has 3-5+ years of hands on relevant experience with rodents
  • Advanced skills on handling, restraining, dosing and performing a variety of procedures on study animals required.
  • Ability to manage large mouse colonies required.
  • Excellent organizational, communication and collaborative skills.
  • Keep accurate records, follow instructions and comply with company policies.
  • Experience with Gene Therapy is a plus
  • Strong organizational skill.
  • Strong self motivation, adaptability and positive attitude.
  • Ability to learn new techniques, and multitask as needed.
  • Excellent record keeping.
  • Excellent writing and verbal communication skills.
  • Experience with animal behavioral paradigms a plus.
The In Vivo Research Associate will be responsible for performing In Vivo studies to support all CNS therapeutic areas and other therapeutic areas of the Non-Clinical department, if needed.

Additional responsibilities include but are not limited to:

• Oversee and perform large numbers of in vivo studies concurrently and according to the experimental designs.

• Perform ICV/Intrathecal/Intraparenchymal/IV/IP/SC injections in mice and rats, monitor animal health, collect blood samples, collect CSF perform necropsies.

• Perform behavioral studies, brain surgeries as required.

• Maintain mouse breeding colonies.

• Ensure accurate data recording.

• General supplies and reagent inventory and ordering.

• Interact with CNS team scientists and provide constant feedback.

• Work cross functionally with liver and ocular teams and provide support to other R&D In Vivo needs.

Responsibilities

Perform In Vivo experiments and animal monitoring according to applicable regulations in support of the CNS team and other therapeutic areas.

Maintain accurate record of procedures and provide results/comments to study directors

Education and Experience Requirements

• Bachelor’s degree in relevant field and 3 years hands on experience with rodents required or equivalent experience is acceptable. Master’s degree preferred.

• Generally, has 3-5+ years of hands on relevant experience with rodents

• Advanced skills on handling, restraining, dosing and performing a variety of procedures on study animals required.

• Ability to manage large mouse colonies required.

• Excellent organizational, communication and collaborative skills.

• Keep accurate records, follow instructions and comply with company policies.

• Experience with Gene Therapy is a plus.

Key Skills, Abilities, and Competencies

• Strong organizational skills.

• Strong self-motivation, adaptability and positive attitude.

• Ability to learn new techniques and multitask as needed.

• Excellent record keeping.

• Excellent writing and verbal communication skills.

• Experience with animal behavioral paradigms a plus.

Complexity and Problem Solving

• Demonstrate independent problem solving skills of technical issues; develop solutions to a variety of moderate to complex problems; Discuss with supervisor and refer to policies/practices for guidance.

• Must be comfortable in the fast-paced, biotech start-up environment and interact with multi-disciplinary research teams at Spark.

• Exercise judgment within defined procedures and practices to determine appropriate action.

Please be aware that Spark mandates COVID-19 vaccination of all employees regardless of work location. Accommodations may be made in accordance with applicable law.


Nearest Major Market: Philadelphia



Join the Spark Team

We were born of innovation, springing from the curiosity, imagination and dedication of remarkable scientists and healthcare visionaries. Our shared mission is to challenge the inevitability of genetic disease by discovering, developing, and delivering treatments in ways unimaginable - until now.

We don't follow footsteps. We create the path.

Company

At Spark Therapeutics, a fully integrated, commercial company committed to discovering, developing and delivering gene therapies, we challenge the inevitability of genetic diseases, including blindness, hemophilia, lysosomal storage disorders and neurodegenerative diseases.

Founded in March 2013 as a result of the technology and know-how accumulated over two decades at Children’s Hospital of Philadelphia (CHOP), our investigational therapies have the potential to provide long-lasting effects, dramatically and positively changing the lives of patients with conditions where no, or only palliative, therapies exist. Greater understanding of the human genome and genetic abnormalities have allowed our scientists to tailor investigational therapies to patients suffering from very specific genetic diseases. This approach holds great promise in developing effective treatments to a host of inherited diseases. Our initial focus is on treating orphan diseases.

Headquartered in dynamic Philadelphia, we are a diverse, experienced team united in our goal to break down barriers for people and families affected by genetic diseases. As our name suggests, our investigational, one-time therapies are designed to spark healthy biology, and deliver potentially life-altering transformation for people and families affected by genetic disease. Spark is a member of the Roche Group.

Find Us
Website:
Telephone
215-989-1149
Location
3737 Market Street
Suite 1300
Philadelphia
PA
19104
United States

Get job alerts

Create a job alert and receive personalized job recommendations straight to your inbox.

Create alert