Non-Clinical Research, In Vivo Research Associate (CNS)
- Employer
- Spark Therapeutics
- Location
- Pipersville, Pennsylvania
- Salary
- Salary not provided
- Closing date
- Mar 5, 2022
View more
- Discipline
- Health Sciences, Clinical Research, Drug Development
- Job Type
- Research Scientist
- Organization Type
- All Industry, Biotech
Job Details
The In Vivo Research Associate will be responsible for performing In Vivo studies to support all CNS therapeutic areas and other therapeutic areas of the Non-Clinical department, if needed.
Additional responsibilities include but are not limited to:
- Oversee and perform large numbers of in vivo studies concurrently and according to the experimental designs.
- Perform ICV/Intrathecal/Intraparenchymal/IV/IP/SC injections in mice and rats, monitor animal health, collect blood samples, collect CSF perform necropsies.
- Perform behavioral studies, brain surgeries as required.
- Maintain mouse breeding colonies.
- Ensure accurate data recording.
- General supplies and reagent inventory and ordering.
- Interact with CNS team scientists and provide constant feedback.
- Work crossfunctionally with liver and ocular teams and provide support to other R&D In Vivo needs.
Perform In Vivo experiments and animal monitoring according to applicable regulations in support of the CNS team and other therapeutic areas.
Maintain accurate record of procedures and provide results/comments to study directors
Education and Experience Requirements
- Bachelor’s degree in relevant field and 3 years hands on experience with rodents required or equivalent experience is acceptable. Master’s degree preferred.
- Generally has 3-5+ years of hands on relevant experience with rodents
- Advanced skills on handling, restraining, dosing and performing a variety of procedures on study animals required.
- Ability to manage large mouse colonies required.
- Excellent organizational, communication and collaborative skills.
- Keep accurate records, follow instructions and comply with company policies.
- Experience with Gene Therapy is a plus
- Strong organizational skill.
- Strong self motivation, adaptability and positive attitude.
- Ability to learn new techniques, and multitask as needed.
- Excellent record keeping.
- Excellent writing and verbal communication skills.
- Experience with animal behavioral paradigms a plus.
Please be aware that Spark mandates COVID-19 vaccination of all employees regardless of work location. Accommodations may be made in accordance with applicable law.
Nearest Major Market: Philadelphia
Join the Spark Team
We were born of innovation, springing from the curiosity, imagination and dedication of remarkable scientists and healthcare visionaries. Our shared mission is to challenge the inevitability of genetic disease by discovering, developing, and delivering treatments in ways unimaginable - until now.
We don't follow footsteps. We create the path.
Company
At Spark Therapeutics, a fully integrated, commercial company committed to discovering, developing and delivering gene therapies, we challenge the inevitability of genetic diseases, including blindness, hemophilia, lysosomal storage disorders and neurodegenerative diseases.
Founded in March 2013 as a result of the technology and know-how accumulated over two decades at Children’s Hospital of Philadelphia (CHOP), our investigational therapies have the potential to provide long-lasting effects, dramatically and positively changing the lives of patients with conditions where no, or only palliative, therapies exist. Greater understanding of the human genome and genetic abnormalities have allowed our scientists to tailor investigational therapies to patients suffering from very specific genetic diseases. This approach holds great promise in developing effective treatments to a host of inherited diseases. Our initial focus is on treating orphan diseases.
Headquartered in dynamic Philadelphia, we are a diverse, experienced team united in our goal to break down barriers for people and families affected by genetic diseases. As our name suggests, our investigational, one-time therapies are designed to spark healthy biology, and deliver potentially life-altering transformation for people and families affected by genetic disease. Spark is a member of the Roche Group.
- Website
- http://sparktx.com/
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