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Laboratory Manager CNS Research

Employer
Spark Therapeutics
Location
Philadelphia, Pennsylvania
Salary
Salary not provided
Closing date
Nov 1, 2021

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Job Details

Primary Duties

Manage the day-to-day operational support activities of the R&D laboratory, inclusive of all CNS scientific groups, GLP and non-GLP related. Responsible to develop plans and implement procedures to increase laboratory efficiencies.

• Champion the adoption of all safety initiatives and ensure daily compliance.

• Assist with onboarding by training new hires on processes in place within the CNS Team and across the organization.

• Assist with training new hires on routine experimental procedure in cell and molecular biology.

• Participate in experimental activities to help a team meet a deadline.

• Coordinating and performing samples shipping/receiving.

• Assist with equipment-related tasks, including organizing on-side training, scheduling installation and maintenance.

• Act as point person to coordinate the purchase of all laboratory equipment, collaborating with scientific staff, procurement, metrology, engineering, IT and facilities.

• Responsible for short and long-term planning for all aspects of lab support operations as they relate to the scientific pipeline, maintaining focus on scientific goals.

• Provide feedback as to the availability of adequate operational personnel, space, equipment, and facilities to meet scientific goals.

• Play a strong role in the collaborative efforts of the R&D Operations team effecting LIMS administration, lab support/maintenance, sample management, laboratory efficiency initiatives

• Communicate laboratory requirements with the Facilities, Metrology, IT and Engineering teams.

Responsibilities

• Support the CNS Team at lab management level

• Prioritize and facilitate day-to-day activities to support R&D laboratory functionality.

• Develop, implement, and maintain procedures to increase efficiencies in the laboratory.

• Accountable to manage Sparks ordering processes for laboratory equipment.

• Coordinate laboratory logistics effecting safety practices, reagents, samples, chemicals, waste handling, equipment procurement. Request internal or third-party support as needed.

• Communicate laboratory requirements to secure appropriate support for efficiency initiatives. Support CNS Team experimentally by training new hires on routine protocols and by performing routine protocols to help a Team reach a goal.

• Collaborate with Sample Management, R&D Operations, LIMS, EHS, IT and Lab Management to support CNS Team day-to-day activities.

• Participate in meetings and activities related to research, including weekly lab meetings and small group research meetings. Provide system operation training to new staff, as needed.

Education and Experience Requirements

• Bachelor’s degree required; MS in a relevant field preferred.

• Minimum 5-8+ years of biotech industry working experience.

• Project management or supervisory experience strongly preferred.

• Broad understanding of laboratory technical and equipment needs; hands-on experience with microscopy, standard molecular and cell biology techniques such as DNA cloning, qPCR, ELISA, flow cytometry, cell culture, etc., preferred.

• Basic knowledge of building systems requirements preferred.

Key Skills, Abilities, and Competencies

• Strong organizational skills and working experience in Biotech industry.

• Multiple projects oriented.

• Excellent writing and verbal communication skills.

• Ability to analyze and troubleshoot experiments.

• Ability to manage competing priorities in a fast-paced environment.

• Independently motivated and exceptionally detail oriented.

• Ability to learn new techniques and work independently after training

Complexity and Problem Solving

• Demonstrate independent problem-solving skills for technical issues; develop solutions to a variety of moderate to complex problems; Discuss with supervisor and refer to policies/practices for guidance.

• Must be comfortable in the fast-paced, biotech start-up environment and interact with multi-disciplinary research teams at Spark.

• Exercise judgment within defined procedures and practices to determine appropriate action.

Please be aware that Spark mandates COVID-19 vaccination of all employees regardless of work location. Accommodations may be made in accordance with applicable law.


Nearest Major Market: Philadelphia



Join the Spark Team

We were born of innovation, springing from the curiosity, imagination and dedication of remarkable scientists and healthcare visionaries. Our shared mission is to challenge the inevitability of genetic disease by discovering, developing, and delivering treatments in ways unimaginable - until now.

We don't follow footsteps. We create the path.

Company

At Spark Therapeutics, a fully integrated, commercial company committed to discovering, developing and delivering gene therapies, we challenge the inevitability of genetic diseases, including blindness, hemophilia, lysosomal storage disorders and neurodegenerative diseases.

Founded in March 2013 as a result of the technology and know-how accumulated over two decades at Children’s Hospital of Philadelphia (CHOP), our investigational therapies have the potential to provide long-lasting effects, dramatically and positively changing the lives of patients with conditions where no, or only palliative, therapies exist. Greater understanding of the human genome and genetic abnormalities have allowed our scientists to tailor investigational therapies to patients suffering from very specific genetic diseases. This approach holds great promise in developing effective treatments to a host of inherited diseases. Our initial focus is on treating orphan diseases.

Headquartered in dynamic Philadelphia, we are a diverse, experienced team united in our goal to break down barriers for people and families affected by genetic diseases. As our name suggests, our investigational, one-time therapies are designed to spark healthy biology, and deliver potentially life-altering transformation for people and families affected by genetic disease. Spark is a member of the Roche Group.

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