Computational Geneticist

The Frazer and Gymrek labs are looking for highly motivated postdocs or senior scientists to work as part of the newly funded Center for Admixture Science and Technology (CAST) at UC San Diego. You will work with large genetic datasets, such as the UK BioBank, GTEx, All of Us (AoU) and the Million Veterans Program (MVP) to characterize the associations between genetic variation and disease in global and local ancestry-aware settings. The overarching goal of the project is to examine how complex interactions between genetics, individual behavior, socioeconomic status and the environment influence health in admixed individuals. You will develop new methods that incorporate local ancestry and complex variants (including tandem repeats and HLA types) in multivariate models and polygenic risk score (PRS) calculations, which will be benchmarked to determine accuracy across ancestries and admixed individuals. We hope to recruit promising early career scientists who have the background and expertise to contribute exciting ideas and advance this complex research project.

Applicants should hold a PhD in a relevant research area such as genetics, genomics and bioinformatics. Degrees in computer science and biology with experience in bioinformatics will be considered as well. In addition to research work, the Postdoc fellow will also participate in grant applications, project management and student training.

Salary commensurate with experience.

Candidates should send a cover letter describing their scientific experiences, their CV and bibliography, as well as contact information for 3 references to Kelly Frazer ( kafrazer@health.ucsd.edu ) or Melissa Gymrek ( mgymrek@ucsd.edu ).





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