Research Associate - Discovery Research

Primary Duties

The Research Associate is a member of the Discovery Group within Spark’s research organization and will support laboratory efforts towards the development and testing of novel gene therapy products. He/she will be responsible for:

• Executing molecular biology and in vitro experiments (e.g., DNA cloning, qPCR, western blot, cell culture).
• Performing routine assays across different discovery programs (e.g., ELISA, MSD/luminex multiplex assays).
• Analyzing and documenting assay results in an electronic lab notebook, technical documents, and other reporting formats.
• Assisting with the development and implementation of new assays (e.g., cell-based, enzymatic, immunoassays). Optimizing existing assays based on in-depth knowledge of laboratory techniques.

Responsibilities

Job Function and Description

75%

Plan, prepare, and perform experiments on the bench to support Discovery Research projects. Assist research staff in the execution of experiments and general laboratory tasks as needed.

20%

Prepare sample analysis reports and accurately document work in electronic lab notebook

5%

Participate in group meetings, scientific discussions, and experiment troubleshooting.

Education and Experience Requirements

• BA/BS in biological sciences required.
• Generally, has 3-5 years of relevant experience
• Strong understanding of the technical and equipment needs in a lab. Significant hands-on experience with standard molecular and cell biology techniques.

Key Skills, Abilities, and Competencies

• Experience in general and advanced lab techniques such as DNA cloning, PCR, SDS-PAGE/western blot, qPCR, ELISA, multiplex biomarker assays, plasmid design and construction, cell culture, reporter assays, etc.
• Proven ability to work independently in hands-on laboratory setting, self-motivated to learn and develop new techniques, perform multiple tasks simultaneously, keep accurate records, follow instructions, and comply with company policies.
• Strong organizational skills.
• Excellent communication skills (both oral and written).
• Works with colleagues as a team player.
• Familiarity of Electronic Lab Notebook (ELN) and Laboratory Information Management Systems (LIMS) a plus.

Please be aware that Spark mandates COVID-19 vaccination of all employees regardless of work location. Accommodations may be made in accordance with applicable law.

Nearest Major Market: Philadelphia

Join the Spark Team

We were born of innovation, springing from the curiosity, imagination and dedication of remarkable scientists and healthcare visionaries. Our shared mission is to challenge the inevitability of genetic disease by discovering, developing, and delivering treatments in ways unimaginable - until now.

We don't follow footsteps. We create the path.