Postdoctoral fellow—Gene transcription

Denver, Colorado (US)
Position is paid in accordance with NIH Scale
October 26 2021
Position Type
Full Time
Organization Type

The Huang Lab at National Jewish health is seeking a talented, highly motivated Postdoctoral Fellow to study super-enhancers in hyper-transcription of cytokine and chemokine genes in inflammation and infection. Our lab uses Next Generation Sequencing  (Nat Commun, 2021, 10.1038/s41467-020-20766-0) to identify potential super-enhancers in response to inflammation and infection, use high throughput enhancer barcoded reporters to assess enhancer activity, and uses 4 color sgRNA guides to delete desired enhancers in cell lines, primary cells and mice to determine the function of the enhancers. Candidates should have a recent Ph.D. degree or expect a Ph.D. degree in 2022 in molecular immunology or molecular biology. Experience with molecular cloning, RNA and DNA isolation, RT-qPCR,  and cell culture is required. Experience with CRISPR, ChIP, and western blot, and Next Generation Sequencing is highly desired. Compensation will be determined according to NIH postdoctoral stipends. 

For questions regarding the position, please contact Dr. Hua Huang at 

Hua Huang M.B., Ph.D.
Department of Immunology and Genomic Medicine, National Jewish Health, 
Department of Immunology and Microbiology, University of Colorado School of Medicine, 1400 Jackson Street, K511a, Denver, CO 80206.

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