Principal Scientist, Chemical Development Informatics

Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.

What You Will Achieve

As a member of our Digital Lab team, you will utilize your experience and knowledge of chemical development technologies, tools and platforms to improve how Chemical Research and Development (CRD) scientists interact with the platforms and the data that drives our science. You will have impact on all phases of CRD operations, from new and improved processes for data entry (inside and outside the lab) through data use (project decisions and regulatory filings) and reuse (modeling and prediction). Working collaboratively with digital lab colleagues across CRD and Pharmaceutical Sciences, you will help shape current and future digital lab strategies and innovative digital solutions to enable CRD scientists and engineers to realize improvements in all areas of their work. You will be actively involved in education efforts to members of the CRD community as you evangelize and advance our digital culture across our organization.

It is your understanding of practical and innovative ways for scientists to interact with digital systems and your ability to effectively bring enabling digital solutions to scientists that will help in making Pfizer ready to achieve new milestones and help patients across the globe.

How You Will Achieve It

• Design, implement, support, and evolve digital and informatics solutions and platforms for CRD scientists to support scientific experimentation, modeling, and data extraction for various purposes, including continuous improvement efforts, regulatory activities, and audits.
  
• Develop requirements and deliver digital technology to CRD through Pfizer project teams (both self-developed and Pfizer Digital-developed solutions) and through external scientific solution providers.
  
• Assume business ownership over existing and/or new informatics/technology platforms and support the platforms through engagement with business, technical and governance teams.
  
• Educate and support scientists on existing and new technology, which includes formal and informal training, outreach, and ad-hoc support.
  
• Develop and maintain relationships with key technology providers and industry pre-competitive alliances to further technology development of interest to CRD.
  
• Manage informatics systems, including configuration, customization, and administration.
  
• Communicate appropriately on activities and progress to management and key stakeholders.
  
• Take personal responsibility for own work, pushing self and others to exceed goals and deliver results.
  

Qualifications

Must-Have

• A bachelor's degree in Chemistry, Chemical Engineering, or related field relevant to chemical development in the pharmaceutical industry is required.
  
• Experience in a laboratory informatics/scientific informatics role. Experience with enterprise informatics systems is required, and experience with validated systems is desirable.
  
• 3+ years of laboratory experience in a pharmaceutical development organization, with demonstrated involvement in the use of modern development technologies and experimental processes (e.g. DoE, modeling). Experience with GxP/regulatory documentation and/or filings is highly desirable..
  
• Experience using/administering laboratory information/informatics systems, which may include electronic lab notebooks, lab reactor control software, chromatographic data systems, and instrument control systems used in chemistry, chemical engineering, crystallization, and screening disciplines.
  
• Relevant experience in data aggregation, extraction and processing tools and visualization of scientific data using industry-standard software platforms, such as Spotfire, Pipeline Pilot or Tableau. Expertise with BIOVIA laboratory informatics software is highly preferred.
  
• Domain-specific (scientific informatics) programming experience is highly desirable; this may include platforms like Jupyter Notebooks, Pipeline Pilot and/or MatLab.
  
• Small molecule chemistry informatics experience (structure and substructure searching, manipulation, property calculations, analytics).
  
• Demonstrated interest in user interface design and implementation, specifically around scientific practicesand data flow.
  

Nice-to-Have

• A degree, certification or documented achievements in Computer Science, Data Science or a related field.
  
• Synthetic organic chemistry laboratory experience in a research laboratory setting and expertise in process research and process development
  

PHYSICAL/MENTAL REQUIREMENTS

• Ability to work for extended hours at a computer.
  
• Ability to utilize data analytics tools to aggregate and perform data analysis on large, chemically-enhanced datasets.
  

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

• This role can accommodate remote a working arrangement with a periodic on-site presence (preferred average of 1 day/week).
  
• Periodic travel to other Pfizer sites (domestic and international) and technical meetings is anticipated.
  

ADDITIONAL JOB INFORMATION:

• Last Date to Apply is October 29, 2021
  
• Relocation Support Available
  
• Eligible for Employee Referral Bonus
  

#LI-PFE

Pfizer requires all U.S. new hires to be fully vaccinated for COVID-19 prior to the first date of employment. As required by applicable law, Pfizer will consider requests for Reasonable Accommodations.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development