Principal Scientist, Analytical Chemistry

Boulder, Colorado
October 23 2021
Position Type
Full Time
Organization Type
Job Type
Staff Scientist
Analytical Chemist, Structure Elucidation and Separations

Role Summary and Responsibilities
Pfizer Boulder R&D (formerly Array Biopharma) is seeking applicants for an analytical chemist who is experienced in separation/purification (HPLC, SFC) and small molecule structure elucidation by NMR spectroscopy.

In this role, the successful candidate will serve as a key resource and contributor to the Medicinal Chemistry department by providing separations and structural elucidation to support Pfizer Boulder R&D drug discovery programs and development pipeline. Work performed in this role includes purification, characterization, and structure elucidation of small molecules and metabolites, as well as analytical chemistry support for process development (e.g., identification of process impurities, drug product degradants, and other unknowns).

The chosen candidate will interact with a diverse group of world-class scientists in a professional work environment and will be focused on making impactful contributions to pipeline projects through NMR problem solving. We are looking for a highly highly-skilled and motivated individual, who, while capable of working independently, understands and value of cross-functional teamwork and our common mission to invent and develop new therapeutic solutions to unmet medical needs.

Basic Qualifications
  • Ph.D. with 4+ years, M.S. with 9+ years' experience or BS with 12+ years experience in chemistry, analytical chemistry or related field
  • Research experience in NMR structure elucidation with a track record of accomplishments in the area of small organic molecule structure elucidation (e.g., pharmaceuticals, natural products, etc.)
  • Basic knowledge of NMR instrumentation, hardware, software, and experimental NMR methodologies. Experience with routine NMR maintenance, cryogen service, and basic troubleshooting.
  • Demonstrated experience in HPLC and/or SFC separation (including chiral separation). This includes experience in the development and optimization of chromatographic methods, as well as instrument upkeep, troubleshooting, and basic maintenance
  • Technically inclined with a willingness to learn basic instrument troubleshooting and maintenance.
  • A working knowledge of organic chemistry; experience in a medicinal or process chemistry environment is highly desirable
  • Experience using modern NMR software packages, including Bruker Topspin™, MestreNova™, and ACD Labs™ is highly desirable
  • IT literate with the ability to manipulate data workflows in a networked environment (e.g., Windows and Linux OS, macros, scripts, etc.)
  • Excellent oral and written communication skills
  • Customer focused and driven to continually work towards technical and process improvements

Additional Job Information:
  • Last Date to Apply: October 28, 2021
  • Relocation support available
  • Eligible for employee referral bonus

For roles based in Colorado :
The annual base salary for this position ranges from $90,500 to $150,900. In addition, this position offers an annual bonus with a target of 15% of the base salary and eligibility to participate in our share based long term incentive program. Benefits offered include a retirement savings plan, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.

Pfizer requires all U.S. new hires to be fully vaccinated for COVID-19 prior to the first date of employment. As required by applicable law, Pfizer will consider requests for Reasonable Accommodations.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

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