Research Assistant I - Genetics

Houston, Texas
October 18 2021
Health Sciences
Organization Type
The Genetics department is a basic science department located in the George and Cynthia Mitchell Basic Sciences Research Building at the world-renowned University of Texas MD Anderson Cancer Center in the heart of the Texas Medical Center. The focus is on advancing knowledge of the molecular genetic mechanisms that regulate normal and abnormal cellular processes.

Cancer cells accumulate detrimental genetic mutations that perturb the function of important proteins they express. Our lab investigates how protein-folding chaperones (a specialized suite of proteins that help mutant proteins to fold and function within cells) influence the accumulation and phenotypic manifestations of cancer mutations. The ultimate goal of this work is to identify new targeting strategies for precision cancer medicine. We are looking for a Research Assistant I, who will make significant contributions towards achieving this goal. Previous training in molecular and/or quantitative biology is preferred.

The Research Assistant I provides responsible technical assistance in support of research projects by completing assignments requiring a basic knowledge of fundamental techniques and practices related to a particular field of academics or research.

  • Assists principal investigator with scientific research projects focused on understanding the impact of protein-folding chaperones on the accumulation of genetic variation and how they relate to cancer evolution and behavior.
  • Functions, under supervision, in the design and initiation of research experiments.
  • These experiments include, but are not limited to, genetic engineering of yeast and cancer cell lines, assessment of cellular drug tolerance in cell culture, chemical genetics, cloning plasmid DNA libraries for high-throughput assays, RT-PCR, Western blotting, immunohistochemistry, protein purification, proteomics, metabolomics, and other approaches.
  • Assists in training and research work activity for assigned laboratory and research personnel.
  • Supervises general laboratory management including the assembly and use of laboratory equipment and implements safety procedures.
  • Assists with basic laboratory techniques and in preparation of media solutions, buffers and reagents.
  • Reads literature and confers with superiors regarding new procedures and modifies them according to the needs of the project.
  • Other duties as assigned


Required: Bachelor's degree, major course work in one of the basic sciences.


Required: No experience.

It is the policy of The University of Texas MD Anderson Cancer Center to provide equal employment opportunity without regard to race, color, religion, age, national origin, sex, gender, sexual orientation, gender identity/expression, disability, protected veteran status, genetic information, or any other basis protected by institutional policy or by federal, state or local laws unless such distinction is required by law.