Postdoctoral Research Fellows (m/f/div)

The Department for “Molecular Genetics of Ageing”
headed by director Prof. Dr. Adam Antebi
is looking for Postdoctoral Research Fellows (m/f/div)
(job code 02-2021)

The Antebi Department for “Molecular Genetics of Ageing” investigates how regulatory net­works govern animal health and life span. We primarily use the round­worm Caenorhabditis elegans and the tur­quoise killi­fish Notho­branchius furzeri as model organisms, as well as cell culture and mouse. The over­arching goals are to reveal con­served, convergent mechanisms of longevity, and to under­stand how immunity, meta­bolism, and quality control mechanisms cooperate in cellular defense. We apply a multi­disciplinary approach combi­ning genetics, systems biology, cell and mole­cular biology, imaging, biochemistry, and mass spectro­metry in order to understand the biology of ageing and age-related disease. In particular, we have a long-standing interest in under­standing how naturally occurring meta­bolites can serve as signal­ling molecules that regulate animal health and life span, and we are using metabo­lomic approaches to identify such factors.

We seek a highly motivated and talented scientist to join our enthusiastic, colla­borative, and diverse team in an out­standing scientific environment to take part in our exciting research.

  Qualifications

The successful applicant will hold a Ph.D. in a relevant research area such as molecular biology, genetics, bio­chemistry, or metabolomics and has a strong track record of accomplish­ment. Prior experience with model organisms (worm, fly, mouse) would be welcome, but is not required. The appli­cant should have a keen interest in the biology of ageing and excellent written and oral communication skills. The working language is English; know­ledge of German is not required.

Research Environment

The Max Planck Institute for Biology of Ageing, Cologne, was founded in 2008 with the aim to under­stand fundamental mechanisms of healthy ageing in various model systems. The institute is part of a net­work of research institutions in the Cologne-Bonn area dedica­ted to research on ageing and age-related disease, consti­tuting a vibrant and collabo­rative environment. Equipped with state-of-the-art tech­nology and excellent core facilities, to which the success­ful candidate will have access, the institute provides out­standing research opportunities for its scientists. At the moment, we host employees from more than 30 diffe­rent nations worldwide.

The employment contract will be based on contracts for the civil service (TVöD Bund, Tarif­vertrag für den öffentlichen Dienst) and will initially be time-limited. The Max Planck Society is committed to employ more dis­abled individuals and especially encourages them to apply. We also seek to increase the number of women in those areas where they are under­represented and particularly encourage them to apply.

Are you interested?

Then please upload your complete application docu­ments, containing a one-page letter with a personal state­ment describing your scientific accomplishments and your interests in our laboratory, your CV and biblio­graphy, as well as contact information for three references, in electronic form as one single PDF file via our online application platform. Applications will be evaluated on a rolling basis until the position is filled.

Informal inquiries are welcome and should be sent to recruitment-AA@age.mpg.de. For further information about the Institute and the Antebi department please see www.age.mpg.de.

Please do consult recent publications from the Antebi department for more information on our scientific projects:

• Annibal, A., Tharyan, R.G., Schonewolff, M.F., Tam, H., Latza, C., Auler, M.M.K., Gronke, S., Partridge, L., Antebi, A. (2021) Regulation by the one carbon folate cycle as a shared metabolic signature of longevity. Nat Commun 12: 3486
• Tharyan, R.G., Annibal, A., Schiffer, I., Laboy, R., Atanassov, I., Weber, A.L., Gerisch, B., Antebi, A. (2020) NFYB-1 regulates mitochondrial function and longevity via lysosomal prosaposin. Nat Metab 2: 387-396
• Kew, C., Huang, W., Fischer, J., Ganesan, R., Robinson, N., Antebi, A. (2020) Evolutionarily conserved regulation of immunity by the splicing factor RNP-6/PUF60. Elife 9: e57591
• Gerisch, B., Tharyan, R.G., Mak, J., Denzel, S.I., Popkes-van Oepen, T., Henn, N., Antebi, A. (2020) HLH-30/TFEB is a Master Regulator of reproductive quiescence. Dev Cell 53: 316-329
• Tiku, V., Jain, C., Raz, Y., Nakamura, S., Heestand, B., Liu, W., Späth, M., Suchiman, H., Eka, D., Müller, R.U., Slagboom, P.E., Partridge, L., and Antebi, A. (2017) Small nucleoli are a cellular hallmark of longevity. Nat Commun 8: 16083.