GSK

Computational Biologist

Employer
GSK
Location
Collegeville, PA
Salary
Competitive
Posted
October 11 2021
Ref
306845
Organization Type
Pharma
Site Name: USA - Pennsylvania - Upper Providence Posted Date: Oct 11 2021 The Tumor Cell Targeting Research Unit (RU) within Oncology R&D is seeking a highly motivated Computational Biologist to join a multidisciplinary team working to discover and develop novel medicines for the treatment of cancer. The successful candidate will be responsible for providing key computational biology support to the unit by integrating and mining public and propriety genomic data, identifying new targets for novel drug development, investigating pathways/networks to identify predictive and pharmacodynamic biomarkers, and understanding the cellular mechanism of lead molecules in the pre-clinical setting. This exceptionally talented individual will be adept at working with large genomic data sets, possess a broad knowledge of genetic and genomic technologies used in cancer research, have an understanding of cancer biology, and be capable of developing innovative approaches to addressing novel questions. You will enjoy working in an engaging, dynamic, fast-paced environment, and be comfortable communicating complex bioinformatic approaches and analyses to a diverse group of scientists. Key Requirements: MS with 5 years of relevant experience or PhD in computational biology, bioinformatics, biology, or a related field. Strong experience with one or more coding language (R, UNIX(Bash or Command Line), Python, Perl, etc) Experience with analysis and processing of various genomic data (e.g., DNA/ RNA-seq, ChIP-seq, Whole Exome-seq, ATAC-seq, scRNA-seq, WGBS, and/or microarray-based methylation). Next Gen Sequencing. Ability to communicate in a clear and concise manner in both written and verbal form. Work effectively in a multidisciplinary team setting. Adept at managing multiple priorities in an efficient and organized manner. A publication record that demonstrates ability to successfully utilize bioinformatic approaches. Preferred Requirements: A scientific background and interest in cancer biology and/or cancer genetics. A practical background in statistics and statistical analysis. Experience in functional genomics analysis (e.g. CRISPRn, CRISPRi, CRISPRa, shRNA libraries) and new target discovery. Demonstrated ability to integrate multiple data types. Direct knowledge of the drug discovery and/or development process. Knowledge and experience utilizing commercially available pathway and network analysis tools/databases especially those utilized in the field of cancer research (e.g., GSEA, MSigDB). In return for your expertise in these critical areas, GSK will offer you the opportunity to showcase your skillset with a leadership that recognizes and rewards talent! #LI GSK If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US). GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class. At GSK, the health and safety of our employees are of paramount importance. As a science-led healthcare company on a mission to get ahead of disease together, we believe that supporting vaccination against COVID-19 is the single best thing we can do in the US to ensure the health and safety of our employees, complementary workers, workplaces, customers, consumers, communities, and the patients we serve. GSK has made the decision to require all US employees to be fully vaccinated against COVID-19, where allowed by state or local law and where vaccine supply is readily available. The only exceptions to this requirement are employees who are approved for an accommodation for religious, medical or disability-related reasons. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site. Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit GSK's Transparency Reporting For the Record site.

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