Postdoctoral Position

New York City, New York (US)
Salary commensurate with experience.
October 12 2021
Position Type
Full Time
Organization Type
Job Type

 Postdoctoral position available to study the genetics of a new form of radiation sensitivity that develops in colorectal cancer upon transition from adenoma to carcinoma. The work entails use of patient-derived organoids (PDOs) generated from biopsy specimens from ongoing neo-adjuvant treatment clinical trials for colorectal cancer. Data to date indicate a specific DNA repair signature defines a subset of patients that are good responders to therapy. Further, pharmacologic manipulation of enzymes in that signature results in substantively-enhanced responses in PDOs. Clinical translation of these efforts is planned. Our work was recently featured at the 2021 Corning Virtual 3D Summit ( summit), an international meeting that focused on use of organoids to investigate human disease in a Panel Discussion: Organoids as Patient Avatars for Personalized Medicine. A video of this panel discussion is available at: summit. Interested candidates please send curriculum vitae to:

Richard Kolesnick MD

Member, Sloan Kettering Institute


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