Investigator, Chemical Biology
Site Name: USA - Pennsylvania - Upper Providence Posted Date: Oct 13 2021 Do you have a profound interest to solve hard biological problems? If so, this role of Investigator would be a great opportunity to consider. As an Investigator within the Chemical Biology group, you will be carrying out experimental work to support initiation and progression of GSK programs and capabilities. You will be influencing the experimental strategies of the team and contributing to establishing a culture and environment of scientific excellence. Responsibilities: Support GSK effort to establish industry-leading, cutting edge Chemical Biology capabilities Empower the Chemical Biology team by designing and implementing experiments to solve biological questions. Maintain high individual lab-based productivity. Contribute to collaborative work with chemists, biochemists, data scientists, chemoproteomics scientists and biologists. Interpret and communicate complex scientific data. Establish personal and professional development goals and outline plan to meet them. Why you? Basic Qualifications: We are looking for professionals with these required skills to achieve our goals: Ph.D. in Immunology, Biotechnology, Biomedical sciences, or related fields with 0 years experience, or Master's degree with 5 years experience, Bachelor's degree with 10 years experience. Experience in mechanistic pharmacology Experience in bioassay development to profile compounds to obtain structure-activity relationships - binding affinity (ELISA, FRET, BRET), high-throughput functional readouts, etc Flow cytometry experience with panel of 8+ colors. Preferred Qualifications: If you have the following characteristics, it would be a plus: Immunology drug discovery experience with diverse target classes, mechanisms, and modalities Familiar with primary cells and tissue processing techniques. Technical experience in multiplex/MSD assay. Develop and conduct in vitro cellular assays to evaluate antibody/protein binding and relevant functional activity. Mass spectrometry practical skills and proteomic workflows experience. Support the development of efficacious PROTACs. Knowledge and understanding of biorthogonal chemistry. Ability to work collaboratively in a multidisciplinary team and be effective in matrix relationships. Deep knowledge of contemporary chemical biology techniques and literature. Self-starter, proactive with a track record of high productivity and ability to manage multiple tasks simultaneously. Eagerness to grow and develop as a scientist. Why GSK? Our values and expectations are at the heart of everything we do and form an important part of our culture. These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities: Operating at pace and agile decision-making - using evidence and applying judgement to balance pace, rigour and risk. Committed to delivering high quality results, overcoming challenges, focusing on what matters, execution. Continuously looking for opportunities to learn, build skills and share learning. Sustaining energy and well-being Building strong relationships and collaboration, honest and open conversations. Budgeting and cost-consciousness *LI-GSK If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US). GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class. At GSK, the health and safety of our employees are of paramount importance. As a science-led healthcare company on a mission to get ahead of disease together, we believe that supporting vaccination against COVID-19 is the single best thing we can do in the US to ensure the health and safety of our employees, complementary workers, workplaces, customers, consumers, communities, and the patients we serve. GSK has made the decision to require all US employees to be fully vaccinated against COVID-19, where allowed by state or local law and where vaccine supply is readily available. The only exceptions to this requirement are employees who are approved for an accommodation for religious, medical or disability-related reasons. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site. Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit GSK's Transparency Reporting For the Record site.