Postdoctoral Researcher, Medicinal Chemistry
Site Name: USA - Pennsylvania - Upper Providence Posted Date: Sep 27 2021 Postdoctoral Researcher, Medicinal Chemistry (Upper Providence, PA) We are currently looking for a highly motivated organic chemist to join our Medicinal Chemistry team in suburban Philadelphia. The successful applicant will gain experience and knowledge in the areas of medicinal chemistry and high-throughput experimentation with a focus on delivering radiopharmaceuticals for in vivo imaging studies. This interdisciplinary role involves development of novel methodologies for introducing radiolabelled isotopes, translating cold label conditions to ‘hot' label settings, and designing and preparing novel PET ligands. The successful applicant will be considered a GSK employee but a co-sponsoring academic investigator at the University of Pennsylvania will also provide input and guidance. It is envisioned that most of the research will be completed at the GSK site in Collegeville PA but some travel and time in the labs at the University of Pennsylvania is also expected. Basic qualifications Scientific Ph.D. in Organic Chemistry, Synthetic Methodology Development, Synthetic Organic Chemistry or Medicinal Chemistry Experience in synthetic chemistry; knowledgeable in the application of new synthetic methodology and execution of multi-step syntheses and demonstrated problem-solving abilities Highly organized with strong attention to detail and a focus on quality results Excellent oral and written communication skills Strong record of peer-reviewed publications, patents, or presentations Values and Expectations Proactive and self-motivated Strong interpersonal skills Excellent written and oral communication skills High learning agility and curiosity to learn and adopt new technologies Preferred qualifications (in addition to basic qualifications) Scientific Experience and strong mechanistic understanding of organometallic and photochemical transformations Experience in both the design and execution of radiochemical synthesis of common PET isotopes Skill in high-throughput experimentation and automated synthesis platforms Data analytics and cheminformatics experience Track record of working effectively in a team environment Values and Expectations Self-aware; seeks ways to improve personal and scientific skills An ability to work with other scientific disciplines to drive results. Key responsibilities may include The individual will be dedicated to translating expertise in organic synthesis to the development of radioligands and harnessing new technologies and/or methodologies to address current deficits in the field The individual applies the principles of medicinal chemistry in the design of radiolabelled pharmaceuticals Job holders are able to react to emerging data and to independently propose a modification of plans for the area of science they are responsible for Job holders use innovative synthetic chemistry to solve problems. In particular, they are expected to routinely employ high throughput chemistry technology to solve chemistry issues Job holders support patents and publications write-ups when appropriate Why GSK GlaxoSmithKline is a world leading research-based pharmaceutical company that combines both individual talent and technical resources to create a platform for the delivery of strong growth in a rapidly changing healthcare market. GlaxoSmithKline is recognized internationally for its innovative approach to drug discovery and development. Our success is built on the collaboration of multi-disciplinary teams of scientists sharing their ideas and expertise. We are seeking proactive chemists to join us in our mission to improve the quality of human life by enabling people to do more, feel better, and live longer. Why You Success in GSK thrives on strong interpersonal skills and practical chemistry skills combined with a curious, inquisitive nature and a passion for science. You are equally passionate about developing yourself, developing new scientific methodologies, pushing the limits of innovation, and learning something new every day. You are an excellent team player, able to work with others either in the lab or in the office as well as within cross-functional teams. You are independent and able to plan and execute your own workload and deliver results. Your science is conducted with integrity, safety, and the highest standards. You pride yourself in your chemistry and enjoy science as much as we do. Where We Are GSK's US R&D Hub is located in Upper Providence, PA in the Philadelphia suburbs. Just 35 miles from Philadelphia International Airport, the Upper Providence site is home to over 3,000 of our R&D staff. With the concentration of such a large number of scientists you will find a culture that inspires innovation and collaboration, emphasizes professional development, and maintains a strong focus on the patients that are at the end of everything we do. GSK enjoys the proximity to renowned educational and medical research institutions in Philadelphia, recently dubbed “Cellicon Valley” for the emergence in the medical research and biotech sector with the city and surrounding areas. Recognized in 2019 by National Geographic as one of America's Top Cities, Philadelphia offers a revolutionary opportunity for you to live, work, and play within a short commute from GSK. GSK is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class. Subject to approval of reasonable request, GSK is a modern employer and offers flexible working hours and conditions. Please take a copy of the Job Description, as this will not be available post closure of the advert. 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