Luster / Moon Labs at Massachusetts General Hospital - Harvard Medical School
A postdoctoral position is immediately available in the laboratories of Drs. Andrew Luster and James Moon at the Center for Immunology and Inflammatory Diseases at Massachusetts General Hospital - Harvard Medical School to study CD4+ T cell responses to SARS-CoV-2 and related coronaviruses. This work is part of a highly collaborative NIH program project spread across several labs in the Boston area to develop next generation pan coronavirus vaccines. Studies will primarily focus on characterization of SARS-CoV-2 antigen-specific CD4+ T cell phenotypes, durability, and cross-reactivity during natural infection and vaccination in human subjects using a variety of T cell assays including AIM (activation-induced marker) expression, peptide:MHC tetramer staining, and single cell RNA-seq transcriptomic and TCR repertoire analyses. Additional studies will involve in vivo modeling of protective immune responses in animals following vaccination with candidate immunogens and modalities. A description of the labs can be found at https://www.massgeneral.org/medicine/ciid/
Candidates must be highly motivated, well organized, technically proficient, critically minded, and able to work independently but collaboratively with others. Candidates must possess a recent PhD, MD, or MD/PhD with a strong background in cellular or molecular immunology. Extra consideration will be given to those with relevant experience with advanced flow cytometry, in vitro T cell assays, mouse modeling, and systems biology.
To apply, email a cover letter describing research interests and career goals, CV, and contact information for 3 references to