Scientist (non-PhD), Tumor Immunogenicity

La Jolla, California
September 20 2021
Position Type
Full Time
Organization Type
Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.

What You Will Achieve

Pfizer Cancer Immunology Discovery (CID) is within the Oncology division of Pfizer Worldwide Research & Development in La Jolla, CA. CID is dedicated to developing new protein and small molecule therapeutics to improve human life by redirecting the immune system against cancer by leveraging cytokine biology. CID researchers apply the latest scientific knowledge and novel approaches to discover truly innovative Immuno-Oncology therapeutics.

We are seeking to hire a non-PhD Scientist for the Tumor Immunogenicity CID group.

How You Will Achieve It

  • Execution of cell-based functional and biochemical assays to select candidate molecules for clinical development.
  • Planning and execution of in vivo mouse studies and ex vivo functional assessments, such as, multi-color flow cytometry, gene expression analyses, and primary cell culture.
  • Analyze, organize, and present results in small and large group meetings.
  • Read relevant scientific literature to aid in experimental design.
  • Contribute to a dynamic, exciting culture that embraces teamwork and innovation.


  • B.S. degree with 6+ years' experience.
  • Experience in the fields of immunology or cell biology.
  • Ability to plan and execute in vitro and/or in vivo/ex vivo experiments with minimal supervision.
  • Expertise in standard immunologic techniques (e.g. ELISA or FACS) and willingness to develop skills in a broad set of cutting-edge techniques.
  • Excellent organization and planning skills, the ability to work in a fast-paced environment independently or as part of a team, good verbal and written communication, and strong motivation with a dedicated work ethic.


  • M.S. degree with 4+ years of experience.
  • Technical expertise with immune cell-based functional assays (e.g. activation, differentiation, proliferation, and suppression assays by using monocyte/ macrophages, T-cells, or dendritic cells).
  • Immune phenotyping tumor associated immune cells from primary mouse tissue samples by high-parameter flow cytometry.
  • Experience in CRISPR technology and lentiviral transduction.
  • Experience with various murine tumor and/or infectious disease models.
  • Experience with human PBMC and mammalian cell culture.

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development


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