Postdoctoral Research Associate
Applications are now being accepted for a postdoctoral research associate position in the laboratory of Dr. Laxman Gangwani in the Center of Emphasis in Neurosciences, Department of Molecular and Translational Medicine at Texas Tech University Health Sciences Center El Paso. Our research group is investigating the molecular mechanisms of neurodegeneration associated with the pathogenesis of neurodegenerative disorders, including spinal muscular atrophy (SMA), amyotrophic lateral sclerosis (ALS), and Alzheimer’s disease (AD). Specific focus is on understanding the molecular mechanisms of R-loop metabolism and R-loop-mediated DNA damage leading to genomic instability and neurodegeneration. We use biochemical, molecular and genetic manipulation methods, and cell-based and genetically modified mouse models.
Candidates with the following qualifications are encouraged to apply. The title of the position will be determined by the qualifications and research experience of the candidate.
- Highly motivated individuals with a Ph.D. or equivalent degree in biology, biochemistry, molecular biology, neurobiology or neuroscience.
- Previous experiences in mammalian cell culture, transfection, recombinant DNA techniques (cloning, PCR), recombinant protein expression and purification, basic molecular and cell biology methods such as immunoprecipitation, western blot, FACS and ELISA. Immunofluorescence microscopy. Gene expression analysis using RT-PCR.
- First author publications in internationally reputed journals in the fields of biochemistry, cell and molecular biology. Excellent writing and oral communication skills.
- Knowledge and experience working with genetically modified murine models, spatiotemporal inactivation of genes. Phenotypic and behavioral analysis. Experience working with differentiation of fibroblasts into iPSCs and neurons. Experience in primary neuron culture, RNA-Seq analysis, genome editing (CRISPR/Cas) and histological methods are preferable but not a must. Prior experience working with neurodegenerative disorders such as SMA, ALS and AD.
TTUHSC El Paso is a newly independent institution with a medical school and graduate school. It is located in the second largest binational metropolitan area on the U.S.-Mexico border. It provides the opportunities and environment for direct intellectual and interpersonal exchanges among scientists, doctors and graduate students on one campus.
The city of El Paso is nestled between the beautiful Franklin Mountains and the Rio Grande River and has over 300 days of sunshine a year. It ranks among the top 10 “Safest Metro Cities in America” in the 2019 SafeWise report. El Paso also is one of the most affordable cities in Texas, and ranks among the top 20 cities with the lowest cost of living in America in 2020 Niche rankings.
To apply, interested candidates should email to email@example.com and include curriculum vitae and a cover letter that describes research interests, motivation for current position and career plans. Candidates should also submit online application at http://careers.texastech.edu and reference the relevant Job Requisition ID: 25628BR.