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POST-DOCTORAL RESEARCH POSITION IN LUNG TRANSPLANT IMMUNOLOGY

Employer
University of Maryland
Location
Baltimore, Maryland (US)
Salary
Salary commensurate with experience.
Closing date
Nov 13, 2021

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Discipline
Life Sciences, Cell Biology, Immunology, Molecular Biology
Position Type
Full Time
Job Type
Postdoc
Organization Type
Academia
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POST-DOCTORAL RESEARCH POSITION IN LUNG TRANSPLANT IMMUNOLOGY

The Krupnick lung transplantation laboratory has recently relocated to the University of Maryland School of Medicine offers several fully funded post-doctoral positions for individuals interested in transplantation to advance an NIH funded effort examining mechanisms of lung transplant tolerance.    It was the first laboratory to describe the mouse model of orthotopic vascularized lung transplantation and has made seminal discoveries contributing to unique pathways of lung transplant tolerance. Successful candidates will join a dynamic research team that is at the cutting edge of lung immunology that combines cellular, molecular as well as imaging tools to discover pathways that regulate lung alloimmune responses. Persons with an interest in translational aspects of research, including drug development for allograft tolerance, would be well-suited to this position.

A few selected publications include:

Murine vascular endothelium activates and induces the generation of allogeneic CD4+25+Foxp3+ regulatory T cells.  J Immunol. 2005 Nov 15;175(10):6265-70.

Orthotopic Mouse Lung Transplantation as Experimental Methodology to Study Transplant and Tumor Biology. Nature Protocols. 2009; 4(1):86-93

Cutting edge: MHC class II expression by pulmonary nonhematopoietic cells plays a critical role in controlling local inflammatory responses. J Immunol. 2010 Oct 1;185(7):3809-13.

Central memory CD8+ T lymphocytes mediate lung allograft acceptance. J Clin Invest. 2014 Mar 3;124(3):1130-43. 

Eosinophils promote inducible NOS-mediated lung allograft acceptance. JCI Insight. 2017 Dec 21;2(24).

Eosinophils Downregulate Lung Alloimmunity by Decreasing TCR Signal Transduction.  JCI Insight. 2019 Jun 6;4(11).

Potential candidates must be self-motivated, have an MD, DVM and/or PhD degree, and an interest in dedicating at least three years to this post-doctoral fellowship. Knowledge of common immunologic techniques, including but not limited to flow cytometry, immunohistochemistry, western blotting as well as basic molecular biology, is a prerequisite. Prior publications in respected peer-reviewed immunologic journals is a requirement.  The ability to work as part of a team is a critical for this position.  University of Maryland School of Medicine, located in Baltimore, Maryland, USA, is one of the world leading research institutions and offers a unique and rich collaborative environment.

Applicants should submit their application curriculum vitae and two references or letters of reference to akrupnick@som.umaryland.edu.   University of Maryland is committed to providing a diverse environment and encourages applications from underrepresented minorities.

  

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