Sr Manufacturing Associate - Cellular Immunotherapy GMP Manufacturing

Location
Duarte, California
Salary
Competitive
Posted
September 09 2021
Ref
10010721-2
Discipline
Life Sciences
Position Type
Full Time
Organization Type
Healthcare/Hospital
About City of Hope
City of Hope, an innovative biomedical research, treatment and educational institution with over 6000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation's leading cancer centers that develops and institutes standards of care for cancer treatment.

Position Summary
Senior Cell Manufacturing Associate position is available in the Cellular Immunotherapy GMP Manufacturing (CIGMC). This is a fast-paced lab involved in cutting edge technology, research and clinical immunotherapeutic programs. New personnel will be trained in project specific techniques and procedures.

Key Responsibilities include:
  • Provide training and mentoring to junior cell manufacturing associates as directed by supervisor.
  • Manufacture and test T cell products, under minimal supervision, following established SOPs in cGMP facility.
  • Application of aseptic techniques.
  • Passage, maintain and cryopreserve cell cultures (e.g., T cell and tumor cell lines).
  • Provide routine lab support and maintenance activities.
  • Develop and adapt new manufacturing procedures and analytical methodology, under limited supervision.
  • Create, review, and revise Standard Operating Procedures as necessary for cell product manufacturing and process development, under limited supervision.
  • Meticulous attention to detail and accuracy in lab work and documentation, strictly following established SOPS, as well as accurate record keeping and lab documentation.
  • Cooperate with Quality Control (QC) and Quality Assurance (QA) groups to ensure the quality of product and cGMP compliance.
  • Assist in internal inspections and audits to ensure compliance with Federal Drug Administration (FDA) regulations and City of Hope and CTPC procedure requirements.
  • Provide guidance and training to junior team members as directed by supervisor.
  • Required to wear pager, or other communication devices, to respond promptly to emergency calls and for critical equipment failure.
  • Complete and maintain all training required by City of Hope and CTPC.
  • Cooperate with other performance improvement and compliance activities within the department and in the institution.
  • Maintains current knowledge of manufacturing/analytical techniques and industry practices.
  • Follows established City of Hope and department policies, procedures, objectives, performance improvement, attendance, safety, environmental, and infection control guidelines, including adherence to the workplace Code of Conduct and Compliance Plan. Practices a high level of integrity and honesty in maintaining confidentiality.
  • Performs other related duties as assigned or requested.


Basic education, experience and skills required for consideration:
  • Bachelor's degree in biological science or related field with 9+ years of relevant work experience. Experience may substitute for minimum education requirements.
  • Extensive hands-on mammalian cell culture experience.
  • Extensive hands-on cGMP experience.
  • Biotechnology or pharmaceutical industry experience.


Preferred education experience and skills:
  • Master's degree in biological science or related field, with at least 8 years of post-degree research experience
  • Supervisory experience of up to 3 years.

Additional Information
  • To protect the health of patients and staff and to comply with new State of California mandates, City of Hope staff are required to show proof of full vaccination by September 30, 2021. Compliance is a condition of employment.

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

#LI-CM

  • Posting Date: May 13, 2021
  • Job Field: Research
  • Employee Status: Regular
  • Shift: Day Job

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