GSK

Senior Scientist, LGR Functional Genomics

Employer
GSK
Location
San Francisco, CA
Salary
Competitive
Posted
August 18 2021
Ref
286788
Organization Type
Pharma
Job Type
Senior Scientist
Site Name: USA - California - San Francisco Posted Date: Aug 18 2021 “Technology is key to our innovation strategy at GSK, and CRISPR is one of the most important technologies of our time.” Dr. Hal Barron - Chief Scientific Officer and President GSK R&D Are you a curious, collaborative, and driven scientist interested in using biology's most powerful new tool to understand the genetic regulators of complex diseases? The Laboratory for Genomic Research (LGR) is a new functional genomics center on the UCSF Mission Bay campus in San Francisco, CA, representing a novel hybrid model that brings together researchers from UC Berkeley, UC San Francisco, and GlaxoSmithKline under a single roof to work on projects both together and independently. The new laboratory will house up to 40 scientists, 12 of whom will be GSK employees working closely with our UC partners to develop and apply CRISPR-Cas based functional genomics technologies to collaborative research projects. The outputs of these projects will be focused on technologies, new drug targets, and elucidating biological mechanisms that will foster both academic and industrial advances. As a GSK laboratory scientist, you will be responsible for supporting collaborative and GSK-only projects at the LGR. Working in a dynamic and innovative academic-industry environment, this laboratory-based role will give you the opportunity to: Apply CRISPR-Cas nuclease, inhibition, and activation-based approaches to target discovery and validation Develop new cell models and assays to address some of biology's toughest questions Work with world-renowned investigators from GSK, UCSF, and Berkeley Support enabling technologies including scRNA-seq, high content imaging, and robotic-enabled pooled and arrayed screening Develop broad expertise and be involved with some of the most important biological research taking place today Why you? Basic Qualifications: We are looking for professionals with these required skills to achieve our goals: Bachelor's or Master's degree in biological or chemical sciences 3 or more years of research experience Bench-facing laboratory experience, including : basic molecular biology techniques and cloning sterile technique and mammalian cell culture skills Preferred Qualifications: If you have the following characteristics, it would be a plus: Genome editing or functional genomics screening experience Fluency with next-generation sequencing techniques (single cell sequencing a plus) Hands-on experience working with primary cells, iPSC-derived cell types, and/or 3D complex cell models (e.g., spheroids, organoids) Lentiviral production and/or cell engineering experience Hands-on experience with advanced imaging modalities including flow cytometry, confocal imaging, and/or high content imaging Experience and interest in working with automation equipment Works well in a team environment Quick and self-motivated learner Strong track record of delivery Excellent verbal and written communication skills Why GSK? Our values and expectations are at the heart of everything we do and form an important part of our culture. These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities: Operating at pace and agile decision-making - using evidence and applying judgement to balance pace, rigour and risk. Committed to delivering high quality results, overcoming challenges, focusing on what matters, execution. Continuously looking for opportunities to learn, build skills and share learning. Sustaining energy and well-being. Building strong relationships and collaboration, honest and open conversations. Budgeting and cost-consciousness. If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US). GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site. Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit GSK's Transparency Reporting For the Record site.

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