Postdoctoral Researcher in Computational Biology

Employer
Medical University of Gdansk
Location
Gdansk (PL)
Salary
13000 - 15000 PLN gross per month
Posted
September 06 2021
Position Type
Full Time
Organization Type
Academia

About the institution: 
The Project/Centre is funded within the International Research Agendas Programme of the Foundation for Polish Science co-financed  by the European Union under the European Regional Development Fund. The 3P-Medicine Lab (Preventive, Personalized, Precision) International Research Agenda is joint unit of Medical University of Gdansk in Poland and Uppsala University in Sweden. The 3P-Medicine Laboratory (personalized, preventive, precision) is a new science center specializing in research on acquired genetic mutations as risk factors for cancer and other diseases. Our center is focused on somatic mutations that occur early in life in seemingly normal cells that eventually contribute to malignant transformation. Primary interest is in common malignancies that are etiologically related to environmental stimuli: breast cancer, colorectal cancer, urinary bladder cancer and prostate cancer. The ultimate goal is to develop genetic screening approach for non-hereditary cancer risk assessment, years before first clinical symptoms become apparent. Our unique collection of clinical samples includes not only primary and metastatic tumors, but also multiple biopsies of macroscopically normal tissue including frozen sections, peripheral blood, viable skin and stromal fibroblasts as well as cryopreserved primary cell cultures.

More about the center:

https://ira3p.mug.edu.pl/

https://www.fnp.org.pl/en/3p-medicine-preventive-personalized-precision/

More about participating universities:

https://www.uu.se/en

https://mug.edu.pl/

Selection type:
The Mieczkowski lab studies cells transitions, cell-cell communications and chromatin transformations. A key focus is the use of computational and experimental approaches to dissect, model, and interrogate the changes in chromatin structure triggered by genetic modifications and/or extracellular stimulations. The group pursues multi-disciplinary projects aiming to uncover patterns in chromatin and gene expression profiles relating to cell state. Members of the group will use state-of-the-art methodology to analyze molecular profiles obtained with genotyping microarrays, massively parallel sequencing of DNA (DNA methylation, ChIP, ATAC-seq etc.), bulk RNA- and single cell RNA-seq, as well as spatial transcriptomics.

We are looking for Postdoctoral Researcher in Computational Biology (f/m/d) - single-cell and spatial transcriptomic analyses of cancer samples.

Job type – junior/senior postdoctoral researcher (depending on the experience)

Position Type – full time

Salary, “gross-gross” 13000 - 15000 PLN per month (commensurate to experience), including health and social insurance and retirement contributions, net 6500 PLN – 7500 PLN per month (1 EUR = 4.55 PLN, 1 USD = 3.8 PLN).

The expected net salary has been calculated based on social insurance and tax collection rates in Poland and assumes no other sources of income.

Discipline - computational biology, bioinformatics

Organization Type, Academia

Key responsibilities include:

1.   Conducting scientific research and developing works commissioned by superiors.

2.   Compliance with quality standards.

3.   Analysis of bulk ‘omic’ and genetic data obtained with NGS.

4.   Analysis of single-cell data.

5.   Preparation of documented code.

6.   Interactions with clinical partners, biobanking and bioinformatics teams.

7.   Preparation of materials for scientific publications and patent applications.

8.   Participation in collaboration with foreign partner (Uppsala University, Sweden).

Research areas – Biological sciences, Computer science, Medical sciences

Requirements

1.   PhD degree: bioinformatic, mathematician, molecular biology or equivalent.

2.   At least one first author article.

3.   Expertise in R or Python

4.   Preference will be given to candidates that have research experience in genome-wide data analyses or with single-cell analyses

5.   Strong interest in interdisciplinary research.

6.   Prior participation in foreign scholarships/training is welcome.

7.   Good knowledge of written and spoken English.

8.   Excellent interpersonal and communication skills.

9.   Ability to work in a team

Application Submission – Required documents:

1.   CV

2.   Motivation letter

3.   References to at least three former or current employers /mentors

Due to the entry into force of Regulation (EU) 2016/679 of the European Parliament and of the Council of 27 April 2016, we also require that your job advertisements include a clause requesting the candidate’s consent to the processing of his or her personal data by the institution which carries out the recruitment process: “I agree to the processing of personal data provided in this document for realizing the recruitment process pursuant to the Personal Data Protection Act of 10 May 2018 (Journal of Laws 2018, item 1000) and in agreement with Regulation (EU) 2016/679 of the European Parliament and of the Council of 27 April 2016 on the protection of natural persons with regard to the processing of personal data and on the free movement of such data, and repealing Directive 95/46/EC (General Data Protection Regulation)”.

Please submit all above documents in a single PDF file.

Deadline of submission – September 30th, 2021

Use: mab@gumed.edu.pl to apply

For more info: jakub.mieczkowski@gumed.edu.pl or +48 58 3491852

About us:
Foundation of Polish Science –  the largest non-governmental organisation supporting science in Poland, under its project: International Research Agendas (IRAP), funded with European Regional Development Fund, seeks candidates for a position of postdoctoral fellow at 3P-Medicine Laboratory – led in Medical University of Gdańsk, Poland with the scientific partner Uppsala University, Sweden by prof. Jan Dumanski and prof. Arkadiusz Piotrowski.

This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No 857533 and from the International Research Agendas Programme of the Foundation for Polish Science co-financed by the European Union under the European Regional Development Fund.

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