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Staff Scientist - Pediatric CAR T Cell Therapies

Employer
City of Hope
Location
Duarte, California
Salary
Competitive
Closing date
Nov 2, 2021

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Discipline
Life Sciences, Cell Biology, Physical Sciences, Chemistry
Position Type
Full Time
Organization Type
Healthcare/Hospital

Job Details

Thank you for your interest. Please note, the purpose of this posting is to recruit for on-going and future positions.

About City of Hope

City of Hope, an innovative biomedical research, treatment and educational institution with over 6000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation's leading cancer centers that develops and institutes standards of care for cancer treatment.

Position Summary

This Project Development Scientist position will be part of the Clinical and Translational Project Development Core supporting project management for a California Institute of Regenerative Medicine (CIRM)-funded clinical trial, grant reporting, future grant submissions and manuscript writing. This Project Development Scientist will be affiliated with a Phase I Clinical Trial led by Dr. Leo D. Wang, focusing on chimeric antigen receptor (CAR) T cell therapies in pediatric populations. S/he will work closely with program-associated laboratory and clinical researchers, regulatory staff and biostatisticians to shepherd projects from conception to grant funding, to clinical trial, to manuscript.

Responsibilities Include:
  • CIRM Project Management: Scientist will manage timelines, all site visits, and quarterly progress reporting for a CIRM CLIN 2 grant funding an ongoing clinical trial of CAR T cells in pediatric neurooncology patients.
  • Develop In-depth Knowledge of Immunotherapy Program Research Goals and Areas of Emphasis: Scientists are expected to become well-versed in the terminology, biology and treatments associated with the Immunotherapy Center and Cellular Therapies program. Scientists will attend Immunotherapy Center Disease Team meetings, Pediatrics Disease Team meetings, Wang laboratory pre-clinical research data meetings, and relevant seminars and conferences to gain a thorough familiarity with the ongoing research interests of the Immunotherapy Center.
  • Project Design and Grant Writing: Scientists will assist and advise in design and preparation of new projects for funding as well as managing the logistics of grant submission. They will help match investigators to appropriate grant opportunities throughout the stages of project and career development. They will edit/write portions of the grant text and frame the project as appropriate for the specific application. They will also assist in preparing grant progress reports for grants that have been awarded.
  • Clinical Protocol Writing and Submission: Scientists will work with the protocol design team (laboratory and clinical investigators, biostatisticians, research nurses, investigational pharmacists) on clinical trial design and protocol preparation for Immunotherapy Center investigator-initiated early-phase clinical trials. Scientists will interface with Research Support Services to develop consent forms. For translational projects involving a City of Hope-held Investigational New Drug Application (IND), they will provide and review text and figures for IND submission.
  • Manuscript Writing and Public Access Compliance: Scientists will advise and assist investigators with interpretation and presentation of clinical / translational data for publication and edit/write portions of the manuscript text. They will also ensure that the appropriate funding agencies and the City of Hope Comprehensive Cancer Center Support Grant are acknowledged, and that NIH-funded manuscripts are archived in PubMed Central.


Basic education, experience and skills required for consideration:
  • PhD in the biological/chemical sciences with at least 2 years' experience / Master's degree with at least 5 years of experience / Bachelor's with at least 8 years of experience in scientific writing, clinical study management, or clinical trial regulatory experience in a healthcare/research/academic environment.


Preferred education, experience, and skills:
  • NIH or DOD research grant writing (R01 level, not post-doctoral fellowships), involvement with human observational or therapeutic studies, protocol design/writing for human sample, observational/retrospective or therapeutic studies, translational project management.
  • Familiarity with data analysis techniques, graphing methods, and interpretation of laboratory and clinical data.


City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

  • Posting Date: May 6, 2021
  • Job Field: Clinical Research
  • Employee Status: Regular
  • Shift: Day Job

Company

City of Hope, an innovative biomedical research, treatment and educational institution with over 5,000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research.  City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation’s 20 leading cancer centers that develops and institutes standards of care for cancer treatment.

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