Postdoc fellow

Exciting postdoctoral training opportunity to study vascular and immune microenvironment and to develop new therapeutics at the University of Pennsylvania

The Fan lab is seeking three postdoctoral fellows to understand molecular mechanisms underlying vascular and immune dysfunction and to develop new therapeutics to treat cancer and heart diseases. 

These NIH-funded positions will aim at deciphering the mechanisms by which tissue microenvironment regulates immunity, tumorigenesis, and cardiac repair (www.med.upenn.edu/fanlab). The postdoc research projects focus on 1) endothelial plasticity in cardiac repair after ischemia (under co-mentorship with Dr. Yangqing Anna Gong, Assistant Professor, Department of Medicine, University of Pennsylvania), 2) genetic and metabolic reprogramming tumor endothelial cells and macrophages to block tumor progression, reverse tumor immune suppression, and overcome tumor resistance to checkpoint blockade and CAR T immunotherapy, and 3) T cell infiltration, activation, and exhaustion in tumor microenvironment.

Highly motivated individuals with a PhD degree in vascular biology, cancer biology, immunology, stem cell biology, or a related area are encouraged to apply. Practical experience with molecular and cellular biology techniques and animal models is required. Preference will be given to recently graduated candidates with strong career motivation. Competitive stipend and a generous benefits package commensurate with experience will be provided according to NIH guideline.

Please email a cover letter, current CV and bibliography, brief statement of research interests, and the names/addresses of 3 references to:

Yi Fan, MD PhD, Associate Professor, Department of Radiation Oncology, Abramson Cancer Center, and Cardiovascular Institute, University of Pennsylvania