This position is in the DNA Repair and Genome stability laboratory investigating fundamental processes of mutagenesis and carcinogenesis. The position seeks a dedicated, innovation-driven individual interested in multi-disciplinary approaches and collaborative research addressing mechanisms of DNA damage and repair in cancer development and treatment. We have several NIH-funded projects focused on epigenetic, chromatin-based regulation of DNA repair pathways and the development of new methodologies enabling genome-wide profiling of mutagenic and carcinogenic DNA adducts. The position provides access to state-of-the-art, modern research laboratory equipment and, offers the unique opportunity to get involved in multiple, collaborative research projects.
- Ph.D. in Molecular Biology, Biochemistry, Cell Biology, or related Biomedical Sciences.
- Strong background and training in molecular biology, cell biology and biochemistry.
- Experience in immunofluorescence, cell cycle analysis, DNA fiber assay, DNA replication is strongly preferred.
- Experience in biological computation/informatics, next-generation sequencing (Illumina, PacBio) is helpful, but not necessary.
- Experience using mammalian cell culture and standard molecular biology techniques is required, additional experience using yeast cells is helpful but not necessary. A background in chromatin biology, DNA repair, next-generation DNA sequencing, and bioinformatics is preferred.
- Strong organizational, written, and verbal communication skills in English. Ability to work independently with minimal oversight from PI.
- Ability to effectively manage research projects.
- Strategic planning, prioritization, and goal setting are required.
- Enthusiasm, self-motivation, and ability to excel in a highly competitive and rapidly evolving cancer research environment.
- Demonstrated scientific productivity, and strong publication record.
- Ability and interests in preparing and submitting competitive fellowship applications.
- The position entails working on multiple projects at any given time.
- Participate in the design, implementation, and evaluation of research studies.
- Collect data and develop data collection procedures; train and supervise data collection personnel.
- Design, organize, and implement project database; analyze data.
- Collaborate on reports and publication of findings.
The Hormel Institute, a biomedical research center of the University of Minnesota, was established in 1942 and has an excellent reputation and long history for producing world-class medical research. The Institute’s research success has resulted in a second major expansion of its research facilities and includes an additional new state-of-the-art laboratory building that opened in January 2016. The Hormel Institute has targeted its cutting-edge research on better ways to prevent, detect, and treat cancer. The Hormel Institute, University of Minnesota is part of the Masonic Cancer Center, University of Minnesota, a National Cancer Institute Comprehensive Cancer Center, and collaborative research partners with global leaders such as Mayo Clinic, MD Anderson, Columbia University, and many more worldwide. The Hormel Institute offers its research scientists complete access to state-of-the-art cutting edge equipment that includes a cryo-electron microscope (Titan Krios and Tecnai G2 Spirit Biotwin); FACS cell sorter; confocal microscopy; flow cytometry; protein crystallography robotics and diffraction system; nano-HPLC-AB SCIEX triple TOF 5600 mass spectrometry; Leica tissue processor, embedder and microtome; real-time PCR instrumentation; 5 racks of Linux GPU supercomputers for computational biology and bioinformatics; spectrophotometers; and Western blot imagers.
Applications: Interested candidates should send their CV, names and contact details of 2-3 referees, and a cover letter.
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