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Postdoctoral Scholar in Cancer Biology/Cancer Genomics University of Chicago

Employer
University of Chicago
Location
University of Chicago
Salary
Competitive, based on experiences
Closing date
Nov 4, 2021

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Postdoctoral Scholar in Cancer Biology/Cancer Genomics

University of Chicago

The Yang Lab is seeking self-motivated individuals with strong background in cancer biology to study genome instability of cancer. The main goal of the lab is to dissect the molecular mechanisms leading to somatic alterations, identify disease-causing events, and understand how the genetic alterations affect treatment response by combining computational and experimental approaches.

The lab is recruiting two postdoctoral scholars, one in experimental biology and another in computational biology. Both positions are based in the Ben May Department for Cancer Research. To learn more about the PI’s research, please visit http://yanglab.me.

The University of Chicago is a global leader in biomedical research and offers unique opportunities for multidisciplinary collaboration. The Biological Sciences Division, the Physical Sciences Division, the Pritzker School of Molecular Engineering, and the University of Chicago Medical Center are all contained within one compact campus. The University and the Comprehensive Cancer Center operate a number of state-of-the-art core facilities including microscopic facility, genome sequencing facility, animal facility, Biostatistics Laboratory, Human Tissue Resource Center, cancer biobank, the Genomic Data Commons (https://gdc-portal.nci.nih.gov/) and many others.

Responsibilities:

The applicants will have the opportunities to tackle cutting edge problems in biomedical field, interact with world class scientists, and gain experiences and develop skillsets for their next career stage. The experimental biologist is expected to design experiments to study the molecular basis of genome instability and its functional consequences in collaboration with bioinformaticians and statisticians. The computational biologist is expected to develop new computational algorithm(s), perform data analysis, collaborate with biologists and physicians. Both postdoctoral scholars will lead multiple projects, work in a multidisciplinary environment and present/publish the results in scientific conferences/journals.

Qualifications for experimental biologist:

  • Ph.D. in molecular biology/cell biology/genetics or related discipline
  • Experiences in molecular cloning and mammalian cell culture
  • Experiences in gene knockdown, knockout and overexpression in cell culture systems
  • Excellent oral and written communication skills
  • Experiences in one or more of the following fields preferred, but not required: CRISPR editing, genome instability, 3D chromatin organization, gene engineering in mouse

Qualifications for computational biologist:

  • Ph.D. in computational biology/bioinformatics/statistics/computer science or related discipline
  • Experiences in Unix/Linux shell
  • Proficient in at least one of the following programming languages: C++, PERL, Python, R, Java
  • Experiences with high-throughput sequencing data (WGS, WES, RNA-Seq, ChIP-Seq) analysis
  • Excellent oral and written communication skills
  • Experiences in one or more of the following fields preferred, but not required: epigenetics, evolutionary biology, systems biology

To apply, please email your CV, two representative publications, contact information for three references to the PI Dr. Lixing Yang (lixingyang@uchicago.edu).

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