Staff Scientist - Analytical Chemistry

Duarte, California
August 02 2021
Position Type
Full Time
Organization Type
About City of Hope

City of Hope, an innovative biomedical research, treatment and educational institution with over 6000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation's leading cancer centers that develops and institutes standards of care for cancer treatment.

Position Summary

The Beckman Research Institute of City of Hope is looking for a talented Staff Scientist to perform several functions as a member of the Analytical Pharmacology Core Facility. The primary role of this Staff Scientist will include operation of the liquid chromatography tandem mass spectrometry (LC-MS/MS) instrumentation available in the core. These efforts will include not only operating the instrument but also assay development, sample preparation, calibration, data analysis, data management/backup and routine maintenance/trouble shooting. In addition, this Staff Scientist will assist the director with the development and validation of new analytical methods for the quantitative analysis of large and small molecules in support of pharmacokinetic and biomarker investigations.

Basic education, experience and skills required for consideration:
  • Ph.D. or M.D/Ph.D. degree in Life Sciences or related discipline with a background within preclinical and clinical pharmacokinetic studies
  • Previous experience using LC-MS/MS instrumentation for quantitative analysis of large and small molecules.
  • Experience with Waters and/or AB Sciex instruments is especially desirable.
  • Other important skills include knowledge of analytical chemistry and experience with instrument controller software programs, like MassLynx┬« and Analyst┬«.
  • Knowledge of the principles of quantitative analysis and familiarity with the FDA's Biomedical Method Validation Guidance for Industry are also preferred.
  • Strong interpersonal, documentation, and organizational skills, and a commitment to providing high-quality analytical chemistry services for users of the core facility are essential.

Additional Information:
  • For more information on Dr. Timothy Synold's research please visit, here .
  • To protect the health of patients and staff and to comply with new State of California mandates, City of Hope staff are required to show proof of full vaccination by September 30, 2021. Compliance is a condition of employment.

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

  • Posting Date: Jun 4, 2021
  • Job Field: Research
  • Employee Status: Regular
  • Shift: Day Job

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