Senior Principal Scientist, Bioinformatics, Molecular Discovery

Cambridge, Massachusetts
August 01 2021
Position Type
Full Time
Organization Type

We are seeking a talented, experienced bioinformatics researcher to join Pfizer's BioMedicine Design organization located in Cambridge, Massachusetts. The successful candidate will join a small team of computational biologists and software engineers to develop a broad array of computational and database tools in support of cutting-edge approaches to early stage biotherapeutic discovery. Areas of active research include monoclonal antibodies, protein therapeutics, gene therapy, and mRNA-based therapeutics.

  • Designing, developing, and maintaining applications to enable capture and analysis of data to accelerate discovery and enable decision making that drives biotherapeutic projects across a broad range of disease areas. This includes processing and analysis of NexGen Sequencing data as well as assay data and the results of predictive AI models.
  • Working within a team of laboratory scientists, data scientists, and internal and external software developers to rapidly specify, implement, and deploy fit-to-purpose software tools.
  • Manage developer project teams to create useful tools in an agile environment

  • Ph.D. and postdoctoral research with 4-8 years of additional industry or academic experience in a related area such as computational biochemistry, bioinformatics, computer science, or a related field.
  • Demonstrated track record of successful implementation of web-based tools for scientific data management and analysis.

  • Strong software development skills ideally including object-oriented programming and full stack web application development.
  • Strong background in molecular biology, biochemistry, or a related field ideally with an understanding of basic immunology and antibody biochemistry.
  • Basic understanding of pharmaceutical discovery process.
  • Understanding of relational database technology and competence with SQL. Ability to design relational schemas to represent real-world data. Ability to design complex queries to generate clear representations of data from complex relational schemas.
  • Ability to design easy to use intuitive user interfaces.
  • Strong interpersonal skills and an ability to work effectively with a broad range of scientists across multiple disciplines
  • Experience leading software teams combining internal and external resources"

Additional Job Information
  • Last Date to Apply: August 6, 2021

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EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development


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