Genomic Data Scientist
Site Name: UK - Hertfordshire - Stevenage, USA - Pennsylvania - Upper Providence Posted Date: Jul 15 2021 We are seeking a genomic data scientist with a track record of supporting innovative, high quality research by managing and analysing large volumes of genetic and genomic data and results in a distributed database and analytical environment. GSK aims to improve the number of successful late stage clinical trials for innovative medicines, by both identifying and advancing drug targets that have strong evidence of a causal role in disease biology. The Human Genetics team leverages major scientific and technological advances, including investment in biobanks linked to large-scale human health databases, cutting-edge informatics platforms, breakthrough understanding of biological pathways, functional genomics capabilities built upon rapid progress in gene editing, and leading industry-academia partnerships, in order to identify the best targets and to continue evaluation of targets through their life in the pipeline. The successful candidate will work in a multidisciplinary, collaborative and scientifically driven environment, interacting with GSK scientists and key academic collaborators to advance drug discovery and clinical development in multiple disease areas. This research will leverage industry-leading data and compute resources, to address important drug discovery and development challenges, to directly impact GSK's R&D pipeline, and to publish in top scientific journals. The selected Genomic Data Architect will: Prototype and mature robust software platforms to efficiently ingest, curate, query and analyze, human genetic, genomic, and clinical/phenotypic data, to inform target selection and validation decisions across a range of disease areas. Leverage the opportunities and efficiencies afforded by access to hybrid cloud-based, distributed ecosystem of technologies Participate in project teams of GSK scientists and external collaborators to develop novel genetic data analyses, providing and following best practices of efficiently work with large volumes of data on modern storage and computational platforms. Guide creative solutions to challenging scientific questions from early proof-of-concept stages to production deployments Develop analytics tools and applications to enhance the productivity of scientists within Human Genetics and across the Research organization. Why you? Basic Qualifications: We are looking for professionals with these required skills to achieve our goals: Masters or equivalent experience in genetics, bioinformatics, or related life sciences applications. Enterprise, industry experience in SQL and either R or Python collaborative software development, with track record of developing production quality software pipelines, applications, or packages/libraries. Experience working in a distributed data and compute environment (e.g. Apache Hadoop ecosystem). Experience with Apache SparkTM is a significant advantage. Experience with collaborative software development Preferred Qualifications: If you have the following characteristics, it would be a plus: Ability to discuss applications of genomic data types and analyses to target identification and prioritization. Experience with data and/or results from large scale genetic association studies (e.g. GWAS or PheWAS) or large scale functional genomic data. Familiarity with Variant-to-Gene approaches, e.g. fine-mapping, colocalization, etc. Excellent communication and influencing skills and developing leadership skills for working with multidisciplinary teams and colleagues with a diverse set of backgrounds and experiences. Why GSK? Our values and expectations are at the heart of everything we do and form an important part of our culture. These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities: Agile and distributed decision-making - using evidence and applying judgement to balance pace, rigour and risk. Managing individual and team performance. Committed to delivering high quality results, overcoming challenges, focusing on what matters, execution. Implementing change initiatives and leading change. Sustaining energy and well-being, building resilience in teams. Continuously looking for opportunities to learn, build skills and share learning both internally and externally. Developing people and building a talent pipeline. Translating strategy into action - a compelling narrative, motivating others, setting objectives and delegation. Building strong relationships and collaboration, managing trusted stakeholder relationships internally and externally. Budgeting and forecasting, commercial and financial acumen. GSKGenetics *LI-GSK If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US). GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. 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