Senior Scientist

Chesterfield, Missouri
July 29 2021
Position Type
Full Time
Organization Type
Job Type
Senior Scientist
Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.


Senior scientist with broad scientific knowledge of antibody generation, protein purification and cell culture/cell banking to join the Operations Group as the Critical Reagent Analytical Lifecycle Lead, will contribute to the reagent characterization efforts across groups lines that support the development of monoclonal antibodies, gene therapies and vaccines and out commercial stake holders.

We are seeking a candidate to join us in building capabilities to lead the industry in the advancement of products to the market through innovation and execution of analytical testing. This position will provide leadership and contribute to oversight of working team members across partner lines will also provide technical counsel to other scientists, organizations, and senior leadership. Critical reagents support the analytical test methods and confirm suitable quality of clinical supplies in a broad biologics' portfolio.

  • Coordinate the generation and characterization of critical bioanalytical reagents with internal and external partners.
  • Provide oversight of critical reagent strategy and road map and ensure that the quality of critical reagents used in cell-based and immunoassays to support a diverse portfolio in varying stages of clinical development.
  • Facilitate reagent lifecycle during drug development, ensuring that adequate reagent supplies are available to support bioanalytical studies.
  • Provide technical expertise and scientific oversight for the generation and characterization reagents; review technical reports and assist with troubleshooting and problem solving, as needed.
  • Partner and collaborate actively with cross-functional teams to discuss and remediate issues pertaining to critical reagents.
  • Collaborate and mentor colleagues on scientific and strategic directions as part of a multi-disciplinary team.


  • PhD with 0+ years of significant, relevant experience
  • M.S. with 7+ years of significant, relevant experience
  • B.S. with 9+ years of significant, relevant experience
  • Excellent verbal presentation skills and outstanding leader behaviors
  • Experience in biotech drug development including creation and lifecycle management of critical reagents used in analytical testing
  • Experience in cGMP labs including delivery of integrated solutions in regulatory environments.
  • Ability to work closely with Pfizer internal & external partners.

  • Comprehensive knowledge and experience in polyclonal and monoclonal antibody generation and characterization.
  • Experience in working with external vendors/ CROs
  • Demonstrated expertise in the development of bioassay and potential impact of critical reagents in these methodologies
  • Have a general knowledge of regulatory guidelines pertaining to reagent qualification

  • Occasional work outside business hours to accommodate other Pfizer sites and partners.
  • Up to 10% travel to Pharm Sci BTx & PGS sites (possible international travel)

Other Job Details:
  • Last Date to Apply for Job: August 11, 2021
  • Eligible for Employee Referral Bonus: YES
  • Eligible for Relocation Assistance: YES


Sunshine Act

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EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development