Postdoctoral Associates in Experimental Brain Ischemia and Colitis Research

Three postdoctoral positions are available in the Department of Anesthesiology at Duke University Medical Center. The projects use murine models of cardiac arrest, ischemic stroke, and colitis. We apply a wide spectrum of approaches, including molecular and immunologic methods, functional imaging, genetically modified mouse models, and behavioral tests.

Self-motivated individuals – who recently obtained a PhD or MD degree – are encouraged to apply. The ideal candidates should be interested in using rodent disease models to study mechanisms and develop potential therapeutics. Experience in mouse behavioral testing and surgical procedures is highly desirable. The applicants must be creative and capable of working independently as well as part of a team, and will be expected to work on several projects in parallel, develop novel ideas in line with the lab projects, analyze data, write manuscripts, and also assist in data collection for manuscripts and grant applications. It is expected that the candidates can follow instructions from the PI and be responsive to research plans in a timely fashion. The candidates must have a strong commitment to research and scientific ethics. The successful candidates will work in a collaborative and dynamic environment with outstanding resources to promote innovative research. The PI will work closely with each postdoc for her/his productivity and success. Specific requirements for each position are listed below.

Position #1 (cardiac arrest): The main project for this position is to understand the immune response after cardiac arrest and resuscitation. The candidates are expected to have a strong background in immunology, and are familiar with various immunologic techniques, such as flow cytometry and ELISA.

Position #2 (ischemic stroke): The main project for this position is to understand the role of the unfolded protein response (UPR) signaling pathway in ischemic stroke. The candidates are expected to have a strong background in molecular biology. Prior experience in mouse stroke models is strongly preferred.

Position #3 (colitis): This project targets neuro-immune responses that modulate intestinal inflammation using newly established genetic mouse models and a clinical study approach. Prerequisite is a solid understanding of intestinal immunity and immunological analysis methodologies.

Interested candidates should provide cover letter, CV and contact information of 2 references. For Position #1 and #2, please send the application to Dr. Wei Yang (weiyang.duke@gmail.com) and for Position #3, please send the application to Dr. Jorn Karhausen (jorn.karhausen@duke.edu).