Postdoctoral Research Fellow - Epigenetics of Stem-Cell Differentiation

Description

The Biology Department at the University of North Dakota seeks a Postdoctoral Research Fellow to work on an NSF-supported project on the epigenetics of stem-cell differentiation. The appointment will be full-time and benefitted. 

The Postdoctoral Research Fellow will work in Dr. Manu’s laboratory (https://manulab.info). Our research is focused on mapping and understanding gene regulatory networks directing the differentiation of hematopoietic progenitor cells into alternative blood cell lineages. We are a highly collaborative and multidisciplinary team developing novel combinations of empirical and computational approaches for understanding gene regulation. We utilize functional genomics approaches such as RNA-Seq, ATAC-Seq, Hi-C, including single-cell versions, as well as genome editing and reporter assays to characterize chromatin states and gene expression during differentiation. These empirical techniques are coupled with machine learning and computational modeling techniques to mechanistically link epigenetic states with gene expression. Ongoing projects vary in scope from analyses of the enhancers of individual genes to broader genome-scale studies of networks composed of many genes. 

The University of North Dakota has a vibrant and collaborative developmental biology and epigenetics community. Our lab is part of an NIH funded Center for Biomedical Research Excellence focused on the epigenetics of development and disease (https://med.und.edu/epigenetics/) hosted at the University of North Dakota and we collaborate with several labs in the center. The Department of Biology and the epigenetics center feature modern molecular biology, genomics, and computational facilities. 

 
Duties & Responsibilities

We seek an independent experimental biologist with a strong interest in developmental/stem-cell biology, gene regulation, and epigenetics and the ability to work collaboratively with other experimentalists and computational scientists. The postdoc will develop and implement projects, utilizing modern genome editing and functional genomics approaches, to investigate the rules by which epigenetic state and transcription factor occupancy determine how complex loci containing multiple enhancers are regulated.  The postdoc will work closely with computational scientists to develop and validate mathematical models and will have the opportunity to learn computational techniques. The postdoc will disseminate the results of their work in the form of manuscripts and conference presentations. Successful candidates will be expected to mentor undergraduate and graduate students and interact with the larger developmental biology and epigenetics community at the University of North Dakota.

Minimum Requirements

• Ph.D. in a developmental, molecular, cellular biology, or related field. Candidates with PhDs in related fields, such as physics, chemistry, or engineering, will also be considered provided they have experience and interest in experimental genetics and molecular biology.
• Successful completion of criminal history records check.

In compliance with federal law, all persons hired will be required to verify identity and eligibility to work in the US and to complete the required employment eligibility verification form upon hire.  This position does not support the sponsorship of visa fees for continued employment.

Preferred Qualifications

• Experience in developmental genetics, gene regulation, and epigenetics.
• Experience with genome engineering techniques and/or functional genomics.
• Experience with bioinformatics/computational biology.

To Apply

Please apply at the University of North Dakota's job site by visiting 

https://prd.hcm.ndus.edu/psp/recruit/EMPLOYEE/HRMS/c/HRS_HRAM_FL.HRS_CG_SEARCH_FL.GBL?Page=HRS_APP_JBPST_FL&Action=U&FOCUS=Applicant&SiteId=1&JobOpeningId=2928236&PostingSeq=1

For full consideration, applications must be received by August 7, 2021 and include the following materials: 

• Cover letter explaining your interest
• Detailed CV
• Contact information for three references

Position is open until filled.

Queries

Please direct any queries to Dr. Manu at manu.manu@und.edu.

Additional Information

All information listed in this position announcement will be used by Human Resources, the Hiring Department, and EO/Title IX for screening, interviewing and selection purposes.

Confidentiality of Application Materials

Pursuant to NDCC 44-04-18.27, applications and any records related to the applications that identify an applicant are confidential, except records related to the finalists of the position, which are open to the public after the search committee has identified the top three finalists who will be invited to campus.

EEO Statement

The University of North Dakota is an Affirmative Action/Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability or other protected characteristic. Women, minorities, veterans, individuals with disabilities, and members of other underrepresented groups are especially encouraged to apply. Applicants are invited to provide information regarding their gender, race and/or ethnicity, veteran’s status and disability status as part of the application process. This information will remain confidential and separate from your application.

Veteran’s Preference

Veterans claiming preference must submit all proof of eligibility by the closing date. Proof of eligibility includes a DD-214 or NGB 22 and if claiming disabled status, a current letter of disability from the VA dated within the last 12 months.

Clery Statement

In compliance with the Jeanne Clery Disclosure of Campus Security Policy and Campus Crime Statistics Act, the University of North Dakota publishes an Annual Security and Fire Safety Report. The report includes the university’s policies, procedures, and programs concerning safety and security, as well as three years’ of crime statistics for our campus. As a prospective employee, you are entitled to a copy of this report. The report and statistical data can be found online at UND.edu. You may also request a paper copy of the report from the UND Police Department located at 3851 Campus Road, Grand Forks, ND, 58202.