Scientist, Downstream Process Development

Kalamazoo, Michigan
July 16 2021
Position Type
Full Time
Organization Type

The position of Scientist - Downstream Process Development will provide individual scientific expertise, as well as working in an interdisciplinary team, to improve Pfizer's commercial and future bioprocesses through biocatalyst selection, reaction engineering, evaluation of immobilization technologies, as well as design and delivery of downstream purification processes. These projects are based on microbial fermentation, biotransformation, biocatalysis or naturally occurring biomolecules.

The Bioprocess Development Group is a group of 24 highly engaged scientists that apply state of the art genetic, microbiological, engineering and analytical technology to support robust lowest cost production of small-molecule active pharmaceutical ingredients (API) via enzymatic and fermentation processes.

  • Develop and improve active ingredient isolation and purification processes to produce bioprocess based pharmaceuticals.
  • Provide engineering insight in support of enzyme activity and functionality improvement projects.
  • Develop optimized enzyme reaction systems potentially including whole cells, lysates or enzyme immobilization.
  • Ensure proper documentation of results and effectively communicate within the team.
  • Be knowledgeable of production technology and processes to be able to assist in the scale up of developed processes and to provide technical support for commercial biopharmaceutical manufacture.
  • Remain current with and champion the implementation of new technologies to ensure we deliver or exceed project targets.
  • Work effectively in a fast-paced, customer-oriented, team-based laboratory environment.
  • Work under general supervision and independently determine and develop experimental programs.

  • BS in biotechnology, bioengineering, biochemical engineering, bioprocess engineering or chemical engineering with a bioprocess emphasis.
  • 2+ years of experience
  • Proven innovative and creative problem solving skills with strong initiative.
  • Takes personal responsibility for own work, pushing self and others to exceed goals and deliver results.
  • Must have demonstrated strong communication skills, both written and oral.
  • Must be able to establish productive colleague relationships which foster collaboration and cooperation. Bioprocess Development Group (BDG), is a team based organization. Good peer relationships are the only way to get projects done and to succeed.
  • Ability to design robust experiments and to accurately analyze, interpret, follow-up and communicate experimental data, conclusions, limitations, and recommendations.
  • Change agile - can effectively cope and excel with change.

  • Experience in industry-based bioprocess research
  • Statistical (i.e. Minitab, JMP) and coding skills (i.e. MATLAB, Python)


Works with genetics, fermentation, analytical and management groups in BDG, as well as frequent interactions with plant-based colleagues. Works with other component groups of the Small Molecule Technology organization, as well as R&D, to foster inter-group knowledge, technology sharing and process implementation.


This is a lab-based position: Frequent standing and walking, frequent detailed manual manipulations, and computer-based work.


First shift position - some weekend work may be required.

Other Job Details:
  • Last Date to Apply for Job: July 21 2021
  • Eligible for Relocation Package: Yes
  • Eligible for Employee Referral Bonus: Yes

Sunshine Act

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EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development