Pfizer

Sr. Associate Scientist, Molecular Biology and AAV Production

Employer
Pfizer
Location
Cambridge, Massachusetts
Salary
Competitive
Posted
July 16 2021
Ref
4818969
Position Type
Full Time
Organization Type
Pharma
ROLE SUMMARY

We are seeking a candidate specializing in molecular biology or viral vector production to work in the BioMedicine Design (BMD) line of the Medicinal Sciences Organization. In this role the candidate will help support all aspects of AAV production including large scale DNA purification, transfections, and AAV purification. The candidate will work with senior scientists within the group to support several AAV initiatives within the organization.

ROLE RESPONSIBILITIES
  • Provide molecular biology support for development and purification of AAV vectors.
  • Provide cell culture and other support for different stages of AAV production.
  • Routinely provide updates at project meetings.
  • Proactively evaluate new technologies and implement new features and functionality into the discovery pipeline.
  • Work with the head of group, project leads, and other senior group members on experimental design and providing data packages with the goal of identifying and advancing best strategies.
  • Successful candidate will be involved in the design and execution of projects with the ability to operate independently.

BASIC QUALIFICATIONS
  • BS/MS degree with 0-3 years of experience in the area of molecular/cell biology, bioengineering or a related field.
  • Hands on experience with a wide range of molecular biology techniques, including large scale DNA purification and sequence analysis.
  • Experience with gene expression quantification (qPCR, RT-qPCR or ddPCR) is desired.
  • Experience in mammalian cell culture, preferably with suspension cells, is required.
  • Strong communication skills, written and oral and ability to work in team.

PREFERRED QUALIFICATIONS
  • Prior experience with gene therapy is highly desirable.
  • Experience handling large (>10L) cell culture volumes preferred.


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    EEO & Employment Eligibility

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    Research and Development

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