Laboratory Operations Manager

Duarte, California
July 14 2021
Life Sciences
Position Type
Full Time
Organization Type
About City of Hope

City of Hope, an innovative biomedical research, treatment and educational institution with over 6000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation's leading cancer centers that develops and institutes standards of care for cancer treatment.

Position Summary

Under Dr. Don Diamond's direction the Laboratory Manager supervises daily Laboratory Operation's procedures, equipment, and facilities in the Department of Hematology & HCT. The procedures may include, but are not limited to, donor specimen processing for clinical trials, assay development for vaccine production, and other studies. The Laboratory Manager works with the staff to maintain the walk-in refrigerator, the liquid nitrogen area, the autoclave room, the tissue culture rooms, GLP, and the general laboratory areas. Laboratory maintenance also includes regular review and implementation of service contracts for the following instruments: the SpectraMax L, ImmunoSpot, qPCR systems, LC/MS, Infinity, FACS Celesta, Symphony, Genius 1050, refrigerators, freezers, centrifuges, and other equipment. Equipment maintenance requires scheduling preventative maintenance with vendors and submitting requests to Facilities for equipment calibration. Maintaining the Diamond Laboratory also includes notifying Facilities of health hazards and requesting for laboratory improvements and equipment repairs.

The Laboratory Manager is involved in several projects simultaneously including ordering supplies, submitting documents for capital expenditure, reviewing quotes, negotiating competitive pricing with vendors, submitting contracts for equipment, and understanding the budget requirements for current projects. The individual is also responsible for procurement including specimen for different projects related to pre-clinical and clinical (Phase I-III) studies. In addition they will implements procedures and utilizes sound judgement to communicate and guide staff. The individual also interacts with other BRI offices including business development, GMP manufacturing, technology licensing, and research finance.

The incumbent has expert knowledge in the areas of research administration and COH policies, procedures, and systems. The Laboratory Manager operates with a working knowledge of management and leadership competencies. Strong interpersonal skills are applied in interacting with Diamond Laboratory staff and staff members from various departments. The position requires a significant degree of independence and ability to make sound professional decisions. This job also requires high organizational skills, self-motivation, creativity, and meticulous documentation.

Key Responsibilities include:

Laboratory Operations
  • Develop laboratory policies and procedures for the operation and management of shared resources in collaboration with Dr. Don Diamond, the Business Manager, the Project Manager, and the Diamond Laboratory staff.
  • Update and maintain all laboratory policies and procedures.
  • Identify compliance issues for review by Dr. Don Diamond and the Project Manager.
  • Review purchase requests and submit requisitions for supplies, services, and equipment within the program's budget.
  • Research and negotiate competitive pricing for consumables, equipment, and services.
  • Research innovative technology, equipment and supplies relevant for laboratory programs.
  • Coordinate clinical trial logistics related to specimen transportation and material transfer.
  • Coordinate capital equipment purchases by obtaining requests from staff, estimate usage and supporting documentation while prioritizing items for evaluation.
  • Procurement of laboratory supplies, equipment, and specimen.
  • Maintain laboratory equipment which includes scheduling preventative maintenance and calibration for equipment as needed.
  • Organize and manage laboratory supply stocks.
  • Work with campus departments including Occupational Safety and Health, Purchasing, Facilities, Accounting, Receiving, Strategic Sourcing and Research Finance to facilitate operations and compliance with internal policies and federal regulations.
  • Review and submit service requests for external assay processing.

Research Programs
  • Work with Dr. Don Diamond, the Business Manager, and the Project Manager to develop and manage programs to foster the research goals of the Diamond Laboratory.
  • Coordinate material exchange between the Diamond Laboratory and external laboratories and vendors.

Department Support and Development
  • Coordinate laboratory coat services and other general laboratory support including but not limited to submitting work orders for equipment and facilities, ordering software and scheduling laboratory maintenance.
  • Manage safety guidelines according to health and safety regulations: maintain chemical inventory, coordinate laboratory safety trainings, and collaborate with Occupational Safety and Health for internal and external audits.
  • Assist Research Business Manager in coordinating new hire onboarding and hardware/software installation.

Budget Management
  • Manage departmental funds, resource allocation, and comprehensive forecasting of average spending.
  • Responsible for review of supplies, service agreements, purchase orders, contract and maintenance agreements.
  • Prepare and develop project budgets using established data.

Basic education, experience and skills required for consideration:
  • A Bachelor's degree in Biology, Biochemistry, Chemical Engineering, MT/ASCP or a related discipline
  • Minimum of 10+ years of hands-on industry or academia experience with human cell and/or tissue-based products, sample processing, aseptic technique, and sample processing platforms.
  • 1-2 years of experience at a lead, supervisory or managerial level.

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

  • Posting Date: Jul 14, 2021
  • Job Field: Research
  • Employee Status: Regular
  • Shift: Day Job

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