Postdoctoral Position in Integrative Muscle Pathophysiology

Indianapolis, Indiana
Commensurate with NIH FY 2021 Stipend levels + benefits
July 09 2021
Position Type
Full Time
Organization Type
Job Type

A postdoctoral position is available in the laboratory of Steven S. Welc in the Department of Anatomy, Cell Biology & Physiology and Indiana Center for Musculoskeletal Health (ICMH) at the Indiana University School of Medicine (IUSM). The successful candidate will join a research group investigating system-to-system cross-talk and integrative cellular interactions that affect skeletal and cardiac muscle pathophysiology and function. Dr. Welc’ s NIH-funded research focuses on paracrine signals produced by fibroblasts that exert regulatory effects on cardiac myocytes in Duchenne muscular dystrophy. The laboratory uses state-of-the-art technologies and tissue-specific mutant mouse models to examine the molecular mechanisms that underlie dystrophin-deficient cardiac remodeling. The project is collaborative and multidisciplinary with excellent opportunities for advanced training and scientific development.

The applicant must be highly self-motivated, able to design and conduct experiments independently, analyze and interpret results, read literature, present work at meetings, write scientific manuscripts, and speak and write fluently in English. Candidates should be able to function well independently and in a small group. US citizens or permanent residents will have the opportunity to compete for NIH-funded training grants, but this is not required.  

Applicants must possess a PhD, MD, or MD/PhD degree and a strong background in biomedical research and preferably musculoskeletal or molecular biology.  Prior work experience in transgenic and knockout mouse models, cardiac phenotyping, molecular and cell biology techniques, cell culture, biochemistry, histology, immunohistochemistry, immunofluorescence, genomics, proteomics and bioinformatics is highly desirable. 

The newly formed Indiana Center for Musculoskeletal Health (ICMH) is home to one of the largest bone and muscle research groups in the world, providing an exciting environment for collaborative musculoskeletal research with ample opportunities for trainees. To learn more about the ICMH:

As the nation’s largest medical school, IUSM is committed to being an institution that not only reflects the diversity of the learners we teach and the patient populations we serve, but also pursues the values of diversity, equity and inclusion that inform academic excellence. We desire candidates who enhance our representational diversity, as well as those whose work contributes to equitable and inclusive learning and working environments for our students, staff, and faculty. IUSM strives to take an anti-racist stance, regularly evaluating and updating its policies, procedures, and practices to confer equitable opportunities for contribution and advancement for all members of our community. We invite individuals who will join us in our mission to advance racial equity to transform health and wellbeing for all throughout the state of Indiana.

Indianapolis is the capital and most populous city in the State of Indiana. It is growing economically thanks to a strong corporate base anchored by the life sciences. Indiana is home to one of the largest concentrations of health sciences companies in the nation. Indianapolis has a sophisticated blend of charm and culture with a wonderful balance of business and leisure. The growing residential base is supported by rich amenities and quality of life – the city possesses a variety of professional sports, arts venues and outdoor recreation areas. Residents of this dynamic city, and surrounding suburbs, enjoy leading educational systems and top-ranked universities, paired with a diverse population. Indianapolis International Airport is a top-ranked international airport, being named “Best Airport in North America” by Airports Council International for many years. For additional information on life in Indy:

Information about the Department of Anatomy, Cell Biology & Physiology is available at:

Information about the Indiana University School of Medicine is available at:

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