Postdoctoral Fellow - NIH Funded Research- Molecular Diagnostics for Precision Medicine

Location
Duarte, California
Salary
Competitive
Posted
May 10 2021
Ref
10010999
Position Type
Full Time
Organization Type
Healthcare/Hospital
About City of Hope

City of Hope, an innovative biomedical research, treatment and educational institution with over 6,000 employees, is dedicated to the prevention and cure of cancer and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

Founded in 1913 and headquartered in Duarte, California, City of Hope is a remarkable non-profit institution, where compassion and advanced care go hand-in-hand with excellence in clinical and scientific research. City of Hope is a National Cancer Institute designated Comprehensive Cancer Center and a founding member of the National Comprehensive Cancer Network, an alliance of the nation's leading cancer centers that develops and institutes standards of care for cancer treatment.

Position Summary

A Postdoctoral Fellow Position is available in the laboratory of Dr. Tijana Jovanovic-Talisman . Biological nanoparticles that are continuously shed by cells - namely extracellular vesicles (EVs) - are an emerging and exciting strategy for performing minimally invasive diagnos es . We seek a Postdoctoral Fellow with experience in cell biology and quantitative microscopy. Because EVs are loaded with disease specific molecules, they represent an excellent source of biomarker s . The project will develop and apply super-resolution microscopy methods to characterize EVs and their content. Specifically, super-resolution imaging will be used to characterize EVs from heart, brain, and immune cells. The approach will be also used to quantify a subpopulation of EVs associated with disease. Ultimately, the goal is to develop a new platform to perform molecular level diagnoses for precision medicine.

Key Responsibilities include:

The Postdoctoral Fellow will purify and manipulate EVs from cultured cells and plasma, perform imaging experiments using single molecule localization microscopy, and complete data analysis to characterize molecular content of extracellular vesicles.

Basic education, experience and skills required for consideration:
  • A Ph.D. degree in Biomedical Sciences, Biophysics, Chemical Engineering or a related discipline is required with no more than 4 years of postdoctoral training.
  • Experience in quantitative microscopy and cell biology.
  • Ability to carry out independent research and prepare manuscripts for publication.
  • Experience with super-resolution microscopy, extracellular vesicles, and MATLAB programing is preferred.


Additional Information:

About Dr. Jovanovic-Talisman: Tijana Jovanovic-Talisman, PhD is an Associate Professor in the Department of Molecular Medicine . Dr. Talisman currently has multiple projects actively supported by the NIH. She and team are investigating biological processes that are critical to the progression of cancer and other diseases by using quantitative single molecule localization microscopy.

For more information on the Jovanovic-Talisman Lab, please click here .

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

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  • Posting Date: Jul 8, 2021
  • Job Field: Research
  • Employee Status: Regular
  • Shift: Day Job

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