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Post Doc roles in HIV-1 host-virus interactions, latency and therapeutics- Kalpana Lab-Genetics

Employer
Albert Einstein College of Medicine
Location
Bronx, New York
Salary
Salary Depends on Experience
Closing date
Jul 31, 2021

View more

Discipline
Life Sciences, Genetics
Position Type
Full Time
Organization Type
Academia
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Post Doctoral Positions in HIV-1 host-virus interactions, latency and therapeutics- Kalpana Laboratory-Genetics



Kalpana Laboratory in the Department of Genetics at the Albert Einstein College of Medicine is seeking to fill a post-doctoral position immediately. Highly motivated PhDs are needed to take part in exciting HIV/AIDS projects.
 

Kalpana laboratory is investigating host-virus interactions of HIV-1 and the mechanism of HIV persistence and latency. These studies are focused on the interaction between integrase and INI1/SMARCB1. Recent NMR structural studies and modeling of the IN-INI1 domain complex have revealed unprecedented RNA mimicry of INI1/SMARCB1 domain (Nature Communications 2021) and have led to the development of novel class of anti-HIV-1 therapeutics. Kalpana laboratory is also investigating of mechanism of HIV-1 persistence using single-cell and single-molecule RNA-FISH and RNA-seq, and the role of INI1/SMARCB1 on HIV-1 transcriptional and post-transcriptional events. In addition, there are opportunities for studying the tumor suppressor function of INI1/SMARCB1 (Acta Neuropathologica 2021) in the hopes of developing better therapeutics for cancer. The individuals to be appointed will have the opportunity to spearhead these exciting projects designed to unravel the molecular mechanisms of HIV/AIDS and Cacner using molecular biology, biochemistry, virology, structural biology and cell biology approaches.

Note that NY state has one of the lowest COVID-19 positivity rating!

Please email Dr. Ganjam V. Kalpana

ganjam.kalpana@einsteinmed.org

Mark Trauner Faculty Scholar in Neuro-Oncology

Professor, Department of Genetics

Professor, Department of Microbiology and Immunology

Albert Einstein College of Medicine, New York
http://www.einstein.yu.edu/faculty/6576/ganjam-kalpana/

 

The candidates should have a PhD in virology, molecular biology, cell biology, biochemistry or a closely related field. Applicants with additional qualifications in structural biology, modeling or other genetic techniques are also encouraged to apply.

Albert Einstein College of Medicine is an EEO employer.

 

Apply Here: https://www.click2apply.net/ozeVzmSPx684SNVPUBXEP

PI138972812

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