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Senior Scientist - LC-MS Protein Characterization

Collegeville, PA
Closing date
Jun 16, 2021

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Health Sciences, Drug Development
Job Type
Senior Scientist
Organization Type
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Site Name: USA - Pennsylvania - Upper Providence Posted Date: Apr 14 2021 The candidate will be primarily responsible for conducting mass spec-based experiments (e.g. LC-MS and LC-MS/MS) and perform the corresponding data analysis for the characterization of therapeutic proteins. The candidate may be expected to develop other analytical and/or biochemical methods to further understand the structure-function relationship of proteins, while supporting biopharmaceutical development from FTIH through commercial. The mass spec group is well equipped with modern instrumentation including Exploris 480, Eclipse Tribrid, Q Exactive Plus, Orbitrap Fusion Tribrid, Synapt G2S with both H/DX and IM, Xevo G2-XS, Orbitrap XL, NanoUPLC, UHPLC and other supporting instrumentation and associated data analysis software. Why you? Basic Qualifications: B.S. with 6+ years of experience or M.S. with at least 2 years of experience in biotech or pharmaceutical industry Hands-on experience in protein characterization and data analysis using mass spectrometry, including intact. reduced LC-MS and peptide mapping LC-MS/MS workflows Hands-on experience and troubleshooting HPLC/UPLC Preferred Qualifications: Scientific and working knowledge in protein structure and function Scientific and working knowledge in glycosylation of proteins and/or glycomics analysis Experience in biopharmaceutical development, supporting FTIH through commercial Motivated with excellent communication skills, both written and verbal. Candidate should be an instinctive team player with excellent people skills. Why GSK? Our values and expectations are at the heart of everything we do and form an important part of our culture. These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities: Operating at pace and agile decision-making - using evidence and applying judgement to balance pace, rigour and risk. Committed to delivering high quality results, overcoming challenges, focusing on what matters, execution. Continuously looking for opportunities to learn, build skills and share learning. Sustaining energy and well-being. Building strong relationships and collaboration, honest and open conversations. Budgeting and cost-consciousness. If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US). GSK is an Equal Opportunity Employer and, in the US, we adhere to Affirmative Action principles. This ensures that all qualified applicants will receive equal consideration for employment without regard to race, color, national origin, religion, sex, pregnancy, marital status, sexual orientation, gender identity/expression, age, disability, genetic information, military service, covered/protected veteran status or any other federal, state or local protected class. Important notice to Employment businesses/ Agencies GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site. Please note that if you are a US Licensed Healthcare Professional or Healthcare Professional as defined by the laws of the state issuing your license, GSK may be required to capture and report expenses GSK incurs, on your behalf, in the event you are afforded an interview for employment. This capture of applicable transfers of value is necessary to ensure GSK's compliance to all federal and state US Transparency requirements. For more information, please visit GSK's Transparency Reporting For the Record site.
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