Associate Scientist (non-PhD), Biochemistry and Cellular Assay Development

La Jolla, California
June 14 2021
Position Type
Full Time
Organization Type
Why Patients Need You

At Pfizer, our focus is to deliver breakthrough medicines that change patients' lives, as evidenced by our outstanding drug portfolio that ranks as one of the best in the world. Research and development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Pfizer scientists are highly committed to discovering and advancing innovative and novel medicines that have a significant impact in major areas of medical need such as cancer and infectious diseases. Whether you contribute to research and development, ensuring drug safety and efficacy, or supporting clinical trials, you will apply cutting edge technology to accelerate and bring the best in class medicines to patients around the world. As a preeminent leader in the pharmaceutical field, we understand that success starts with scientific excellence. That is why we constantly look for researchers who display courage in tackling new areas of drug discovery, seek an equitable training environment that encourages personal growth, and find joy and satisfaction in working on integrated project teams with researchers from across many scientific disciplines.

Role Summary

Pfizer's Oncology Research Unit (ORU) is seeking an Associate Scientist to join our Biochemistry and Quantitative Pharmacology (BQP) group. BQP is an interdisciplinary and highly collaborative team that employs biochemical, cellular, biophysical, and high throughput assays to identify and characterize novel small molecules to support the development of first in class therapeutics. In this role, the candidate will be expected to develop, validate, and execute biochemical and cellular assays, interpret experimental results, and present their research to colleagues as an integral member of the project team. This position will provide the motivated candidate with ample opportunity for scientific growth through exposure to all aspects of the drug discovery process.

Role Responsibilities
  • Work with supervisor to develop, validate, and implement robust biochemical and cellular assays for novel oncology targets
  • Perform routine screening with new and existing assays in medium and high-throughput formats to drive in vitro SAR
  • Analyze, document, and present high-quality data at internal meetings
  • Perform sterile cell culture to grow and maintain multiple cancer cell lines
  • Maintain laboratory instrumentation and follow safe-lab practices
  • Contribute to a culture that prioritizes scientific discovery, pursues excellence, and encourages growth

Basic Qualifications
  • BS Degree in the biological sciences field with 0+ years of experience in and academic or pharmaceutical/biotech environment
  • General knowledge of safe laboratory practices, including some hands-on experience doing basic pipetting, dilutions, etc.
  • Highly productive, motivated to learn, well organized with attention to detail, and able to multi-task
  • Ability to effectively interact, contribute, and communicate with the team
  • Proficient using Microsoft Office and basic data analysis software

Preferred Qualifications
  • Previous experience running high throughput plate-based biochemical and cellular assays such as TR-FRET, NanoBRET, thermal shift, CETSA, Alpha-Screen, HiBit, flow cytometry, Mesoscale/ELISA, etc.
  • Proficient at aseptic cell culture technique
  • Knowledge and understanding of cancer mechanisms including cancer cell cycle regulation or immuno-oncology.
  • Pharmaceutical/Biotech experience

  • Basic job will require both work at the lab bench and analysis time at the computer.
  • Must be able to wear PPE (lab coat/safety shoes/gloves/etc).

  • Eligible for Employee Referral Bonus

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development

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