Site Name: USA - Massachusetts - Cambridge Posted Date: May 10 2021 Are you a scientist with experience and passion for drug discovery and development in the field of Immuno-Oncology? If so, this Investigator role would be an excellent opportunity to consider. The Immuno-Oncology & Combinations Research Unit (IOC RU) within the GSK Oncology organization is seeking an innovative and highly motivated laboratory-based Investigator to support preclinical development of immune-based therapies and validate novel cancer immunotherapies. This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following: Building on your background in immuno-oncology, you will expand state-of-the-art in vitro and ex vivo assay capabilities at a growing GSK site and support novel target identification efforts. Applying a translational mindset, you will cultivate and work in a dynamic and collaborative environment to interrogate mechanisms of action and pharmacology of novel therapeutics, supporting GSK's diverse immuno-oncology pipeline from early discovery to first-time-in-human commitment. We are looking for a proactive team member, who can think out of the box to solve scientific problems, who is open to the ideas of others, and has a deep curiosity and enthusiasm for uncovering novel biology with a translational mind-set. The investigator will be accountable for generating high quality, robust data and must have an ability to work effectively both independently and as part of a multidisciplinary matrix team. Additionally, you will need to be a collegial team player, open to the ideas of others, and embody a truth-seeking and inclusive culture. Why you? Basic Qualifications: Ph.D. in immuno-oncology, biology or related field; post-doctoral training is not required. One or more years of hands on experience with co-culture systems of primary human cells to interrogate immune cell function using flow cytometry, multiplexed cytokine quantification, and transcriptomic readouts. One or more years experience in conducting independent design and analysis of experiments to functionally characterize biologics, small molecules and/or drug combinations. One or more years experience with transcriptomic or proteomic single cell analyses is ideal. Preferred Qualifications: Experience with a wide range of immune cells types, incl. lymphocytes and multiple myeloid cell types, is preferred. Prior experience with isolation, phenotypical and functional characterization of human tumor-infiltrating leukocytes is advantageous. Strong communication skills and ability to contribute in a cross-functional and global environment. Ability to prioritize, manage time efficiently, and implement creative solutions to meet program needs. High degree of independence, proactivity, and a strong sense of accountability. Excellent problem-solving skills including critical and analytical thinking. Hands-on experience to prioritize multiple projects and meet timelines while maintaining attention to detail and setting high performance standards. Ability to understand, interpret, and communicate complex scientific data. Excellent communication and organizational skills, present results at project team meetings and mentor junior scientists. Why GSK? As GSK Focuses On Our Values And Expectations And a Culture Of Innovation, Performance, And Trust, The Successful Candidate Will Demonstrate The Following Capabilities Our values and expectations are at the heart of everything we do and form an important part of our culture. These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities: Operating at pace and agile decision-making - using evidence and applying judgement to balance pace, rigor and risk. Committed to delivering high quality results, overcoming challenges, focusing on what matters, execution. Continuously looking for opportunities to learn, build skills and share learning. Sustaining energy and well-being. Building strong relationships and collaboration, honest and open conversations. Budgeting and cost-consciousness. *This is a job description to aide in the job posting, but does not include all job evaluation details. 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