POSTDOCTORAL RESEARCH FELLOW (GENE DELIVERY)

Employer
University of Hawaii at Manoa
Location
Honolulu, Hawaii
Salary
$5,667 - $6,500 per month + benefits
Posted
June 09 2021
Position Type
Full Time
Organization Type
Academia

Come work with our team in Hawaii on cutting edge gene editing technology development.

Our lab has recently received an R01 grant for $2.4mil (scored as the top 1-percentile of applicants). We also work with an exciting startup called SalioGen Therapeutics who's goal is to take our technologies developed at the bench and turn them into real clinical cures. See their website: https://saliogen.com/

Our lab has recently expanded to 10 members and continues to grow. We have many exciting projects focused on protein rational design and directed evolution. We have a friendly work atmosphere and are located in Honolulu, Hawaii.

LAB WEBSITE: https://www.ibr.hawaii.edu/343-2/jesse-b-owens/

BEGGINING ANNUAL SALARY: $68,000

DUTIES: Forms and leads a rational design project with the purpose of improving transposase gene delivery. Improves the site specificity of targeted integration into the genome by transposases using novel protein engineering methods. Works independently to design own research program and develops research plans. Conducts a wide variety of molecular biology techniques, some of which include: complex plasmid design and construction; lentiviral preparation and transduction; work with bacteriophage; Fluorescence-activated cell sorting (FACS); tissue culture including embryonic stem cell culture, southern and western blotting, and novel assays designed to test DNA binding and targeted insertion by transposases. Troubleshoots problems related to molecular biology. Performs data analysis and data interpretation. Prepares manuscripts and presentations of results for the scientific community and the public. Writes grant proposals. Trains and oversees undergraduate and graduate students. Manages general lab organization and maintenance. Presents data at lab meetings. 

PRIMARY QUALIFICATIONS: EDUCATION/TRAINING:  PhD from an accredited college or university in Cell Biology, Molecular Biology, or related field.  

EXPERIENCE: At least two (2) years of experience working on publications or projects demonstrating proficiency at protein engineering methods in a research laboratory. Evidence of a strong publication history with lead- author publications relating to studies involving integrating vectors or gene therapy techniques.  

ABIL/KNOW/SKILLS: Working knowledge of general principles of cell biology and molecular biology. Working knowledge of molecular biology techniques, such as complex plasmid design and construction, lentiviral preparation and transduction, bacteriophage, FACS, tissue culture, embryonic stem cell culture, and southern and western blotting. Ability to communicate well both orally and in writing. Ability to use common personal computer (PC) software for word processing (e.g., Microsoft Word), and database/spreadsheet (e.g., Microsoft Excel). Ability to organize PowerPoint presentations. Demonstrated ability to work independently, troubleshoot own problems, and generate research plans, publications and grant proposals. Post Offer/Employment Condition: Must be able to complete the UH Title IX training within twelve (12) months from date of hire. Must be able to complete the UH Laboratory Safety training within six (6) months from date of hire.  

PHYSICAL/MEDICAL REQUIREMENTS: Able to lift and carry up to twenty (20) pounds unassisted. 

POLICY AND/OR REGULATORY REQUIREMENTS:  As a condition of employment, employee will be subject to all applicable RCUH policies and procedures and, as applicable, subject to University of Hawai‘i's and/or business entity's policies and procedures. Violation of RCUH's, UH's, or business entity's policies and/or procedures or applicable State or Federal laws and/or regulations may lead to disciplinary action (including, but not limited to possible termination of employment, personal fines, civil and/or criminal penalties, etc.). 

SECONDARY QUALIFICATIONS: Experience in the directed evolution field. Experience performing molecular biology techniques. Demonstrated ability to perform the following: gel electrophoresis, sequence analysis, polymerase chain reaction (PCR) optimization, and T7 assay. INQUIRIES: Dr. Jesse Owens 956-4828 (Oahu). 

APPLICATION REQUIREMENTS: Please go to www.rcuh.com and click on “Job Postings.” You must submit the following documents online to be considered for the position: 1) Cover Letter, 2) Resume, 3) Supervisory References, 4) Copy of Degree(s)/Transcript(s)/Certificate(s). All online applications must be submitted/received by the closing date (11:59 P.M. Hawai‘i Standard Time/RCUH receipt time) as stated on the job posting. If you do not have access to our system and the closing date is imminent, you may send additional documents to rcuh_employment@rcuh.com. If you have questions on the application process and/or need assistance, please call (808)956-7262 or (808)956-0872.  

RCUH’s mission is to support and enhance research, development and training in Hawai‘i, with a focus on the University of Hawai‘i.

Equal Opportunities Employer – Minorities/Women/Disability/Veteran.

 

Apply Here: https://hcmweb.rcuh.com/psp/hcmprd_exapp/EMPLOYEE/HRMS/c/HRS_HRAM.HRS_APP_SCHJOB.GBL?Page=HRS_APP_JBPST&Action=U&FOCUS=Applicant&SiteId=3&JobOpeningId=221268&PostingSeq=1