TB remains a serious global health problem and there is an urgent need for new therapeutic agents. Work within our group focusses on the development of new anti-tubercular agents. The Parish Lab (https://www.linkedin.com/in/tanya-parish-a564056/) is seeking a qualified chemist at the post-doctoral level to conduct synthetic/medicinal chemistry in the area of tuberculosis.
The candidate will work on a research project to develop novel inhibitors of protein secretion in the global human pathogen Mycobacterium tuberculosis. The candidate will be responsible for the design, synthesis and characterization of small molecules for drug discovery, as well as analytical chemistry.
Description of Responsibilities:
• Conduct a research and development project
• Design and implement research plans
• Troubleshoot and solve experimental and technical problems
• To prepare and present papers, reports, and presentations of current research work
• Write manuscripts and assist with grant preparation
• Oversee quality control and data integrity
Specific duties include:
• Design, synthesis, purification and characterization of small molecules as candidate anti-tubercular agents
• Use of analytical chemistry techniques/methods.
• Support of in vitro ADME studies.