Expert Scientist, Structural Biology Lab
Site Name: USA - Maryland - Rockville Posted Date: Jun 7 2021 Are you energized by the challenge of shaping and accelerating the scientific expertise of a biology program? If so, this Lab Head opportunity could be an exciting opportunity to consider. As Manager of a Lab you will be responsible for providing advanced biology expertise to the selected biology group, and to develop and mentor a small group of biology professionals. This role will provide YOU the opportunity to lead key activities to progress YOUR career, these responsibilities include some of the following… To provide expertise in the area of structural biology to guide the design and selection of new target antigens for vaccine development. Provide scientific and technical advice to cross-functional project teams. Maintain expertise in fields of vaccinology, structural biology, and infectious disease through keeping up to date with scientific literature and attending relevant meetings. Determine structures of vaccine antigens and antigen-antibody complexes using structural methodologies. Possesses strong scientific leadership to enable collaboration with key scientific internal and external stakeholders. High-quality written documentation/presentation of work to enable publications of data in peer reviewed journals, patent filings, etc. Supervise students and junior lab personnel as needed Why you? Basic Qualifications: We are looking for professionals with these required skills to achieve our goals: Degree in structural biology, biochemistry, molecular biology, protein engineering or other related discipline Scientific expertise in x-ray crystallography and/or cryo-electron microscopy (Cryo-EM), with strong experience in structure determination is required Expertise with crystallography and/or CryoEM software packages (Phenix/CCP4/PyMol/Moe/Relion/CryoSPARC,SerialEM) in a mixed Linux/Windows computational environment is required Experience in the field of antigen design and protein characterization Knowledge of diverse protein purification methods (e.g. affinity column purification and size exclusion chromatography) and equipment (e.g. AKTA avant system) Fluency in English, spoken and written Preferred Qualifications: If you have the following characteristics, it would be a plus: PhD with 2+ years, MS with 5+ years, or BS degree with 10+ years of experience in research and development, preferably including vaccine research in an industrial, academic or government laboratory settings Demonstrate willingness to spend ~70% of time in the research laboratory Demonstrated ability to conceive and perform independent innovative research Be a self-starter able to handle multiple projects concurrently Ability to efficiently manage uncertainty, changes in priorities and timelines Good knowledge and understanding of GSK Vaccines strategy and objectives, regulatory requirements, as well as competition intelligence and intellectual property aspects. Ability to integrate this knowledge in decisions and recommendations Excellent communication skills, ability to effectively collaborate within multiple project workstreams Strong track-record of scientific publications in peer-reviewed journals, with at least 3 first author research manuscripts Hands-on and extensive experience in bioanalytical and biophysics assays (e.g. ELISA, SDS-PAGE, Western blot, SPR, DSF, DLS) Experience in scientific programming (Unix shells, Python) Experience working with viral glycoproteins and their interactions with host molecules Why GSK? Our values and expectations are at the heart of everything we do and form an important part of our culture. These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities: Operating at pace and agile decision-making - using evidence and applying judgement to balance pace, rigour and risk. Committed to delivering high quality results, overcoming challenges, focusing on what matters, execution. Continuously looking for opportunities to learn, build skills and share learning. Sustaining energy and well-being Building strong relationships and collaboration, honest and open conversations. Budgeting and cost-consciousness #LI-GSK *This is a job description to aide in the job posting, but does not include all job evaluation details. If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US). 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