Scientist, Cellular Immunology and in vivo Sciences - SAM
Site Name: USA - Maryland - Rockville Posted Date: Jun 7 2021 Are you interested in working with a diverse team of vaccines scientists to develop animal models and immunologic assays to screen and evaluate potency, safety and mechanisms of action of vaccine and immunotherapeutic candidates while supporting platform technology development? If so, this Cellular Immunology and In Vivo Sciences Scientist role would be an ideal opportunity for you. As a Cellular Immunology and In Vivo Sciences Scientist, you will have fundamental knowledge of cellular immunology principles and techniques, preclinical animal studies, vaccine-related innate and adaptive immune responses and mechanism of action of vaccines and immunotherapeutic candidates, to provide expertise in vaccine development for GSK projects. This role will provide YOU the opportunity to lead key activities to progress YOUR career. These responsibilities include some of the following: Provide expertise in the areas of immunology and in vivo preclinical animal studies for various GSK projects. Perform immunological assays with a focus on cellular immunology assays such as characterization of vaccine specific T-cell and B-cell subsets and innate immune cells by intracellular cytokine staining (ICS) and multi-parametric flow cytometry (FACS) from mice and non-human primates (NHP), in vitro human immune cell-based assays etc. as they apply to vaccine discovery/development. Acquire and analyze multi-parametric flowcytometry data using DIVA, FlowJo, GraphPad (Prism), Microsoft Office tools and other software for data analysis. Execute a range of experiments/technical studies/tasks independently based on protocol including animal vaccine studies, tissue processing, ICS, FACS, antibody and cytokine assays etc. to evaluate vaccine immunogenicity. Interpret results and communicates to his/her supervisor and/or designs next logical step of experiments based on interpretation of results. Prepares detailed oral or written summaries of results with interpretation for projects/programs. Independently writes specific technical sections of internal and external reports and contributes to scientific papers. Has theoretical and operational knowledge of flow cytometers and other laboratory equipment in own discipline. Experienced in general lab ordering, lab safety and lab management and organization skills. Be a self-starter able to handle multiple projects concurrently. Display an ability to be productive and successful in an intense work environment as a Team Player. Ability to efficiently manage uncertainty, changes in priorities and timelines. Excellent communication and presentation skills, ability to effectively collaborate within multiple project workstreams and stakeholders. Why you? Basic Qualifications: We are looking for professionals with these required skills to achieve our goals: Degree in immunology, biology, life sciences, molecular biology, cell biology, biotechnology or other related discipline. PhD with 0+ years, or MS with 3+ years, or BS with 5+ years of experience in cellular immunology, research and development, preferably including vaccine research in an industrial, academic or government laboratory setting. Preferred Qualifications: If you have the following characteristics, it would be a plus: Prior experience in working with preclinical CRO's and in vivo animal studies. Why GSK? Our values and expectations are at the heart of everything we do and form an important part of our culture. These include Patient focus, Transparency, Respect, Integrity along with Courage, Accountability, Development, and Teamwork. As GSK focuses on our values and expectations and a culture of innovation, performance, and trust, the successful candidate will demonstrate the following capabilities: Agile and distributed decision-making - using evidence and applying judgement to balance pace, rigor and risk, governance and control, managing ambiguity and paradox. Managing individual performance. Creating a performance culture and driving results, prioritisation, execution, delivering performance. Setting strategic direction and leading on-going organisational transformation. Building a resilient organisation. Building strong relationships and collaboration in service of common goals, engaging the organisation and building trusted external networks for mutual benefit. Managing P&L and capital allocation. #LI-GSK If you require an accommodation or other assistance to apply for a job at GSK, please contact the GSK Service Centre at 1-877-694-7547 (US Toll Free) or +1 801 567 5155 (outside US). 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