Staff Scientist

Duarte, California
May 13 2021
Position Type
Full Time
Organization Type
About City of Hope
City of Hope, an innovative biomedical research, treatment and educational institution with over 6,000 employees, is dedicated to the prevention and cure of cancer, type 1 diabetes, type 2 diabetes and other life-threatening diseases and guided by a compassionate, patient-centered philosophy.

City of Hope has one of the most influential type 1 and type 2 diabetes research programs in the world. Our scientists' work has revolutionized the understanding and treatment of the disease and continues today with exciting developments in cell transplantation, gene regulation, immune tolerance and gaining systemic understanding of diabetes as a complex, multifaceted disease.

To learn more about our exciting research and accomplishments in the field of Diabetes, please visit .

Position Summary
A Staff Scientist position is available in Beckman Research Institute of City of Hope. The Staff Scientist series is designed as a step towards faculty transition for highly accomplished and driven research professionals whose primary function is to support the research infrastructure and activities of the institution. Staff Scientists will bring special skills, knowledge and supervisory experience to research programs or institutional core laboratories. Individuals appointed as staff scientists will receive a one-year fixed-term contract.

We are seeking a Staff Scientists to become a part of the research team headed by Dr. Bart Roep, Professor within the Arthur Riggs Diabetes and Metabolism Research Institute. Our research is focused on the development of novel therapeutic entities to cure type 1 diabetes. This candidate will have the unique opportunity of contributing to a translational research program and working with renowned specialists in the fields of immunology, diabetes, and biotechnology. This successful candidate will be exposed to novel proprietary technologies developed at the City of Hope. Some of the key research topics include the development of cellular and molecular therapeutic approaches aiming to target the autoimmune response and protect insulin-producing cells from the inflammatory microenvironment.

Key Responsibilities include:
  • Devise, plan, document and advance basic science and translational projects in the relevant research area.
  • Generate data for grant applications and prepare manuscripts for publication.
  • Work in close collaboration with other team members and external collaborators, including presentation of progress internally or externally.
  • Train and supervise post-doctoral fellows and technical staff.

Qualifications Basic education, experience and skills required for consideration:
  • Ph.D. or M.D/Ph.D. degree in Life Sciences or related discipline
  • Experience in experimental immunology is needed.
  • Candidates should have experience in cell culture, flow cytometry, molecular biology, ELISA and immunohistochemistry.
  • Experience in Enzyme-linked immunospot (ELISpot), Cytokine Secretion Assay, and other lymphocyte function tests are desirable.
  • Notions on monoclonal antibodies (mAbs) purification and conjugation, pharmacokinetics, biodistribution, immunogenicity and toxicology analysis in experimental models are a plus.

Additional Information:
  • Please submit your current CV/resume along with a cover letter highlighting your research accomplishments, a brief statement explaining how your past research ties in with the goals of our laboratory, and future career plans.
  • For more information on Dr. Bart Roep's research, please click here .

City of Hope is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, sex, sexual orientation, gender identity, age, status as a protected veteran, or status as a qualified individual with disability.

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