Senior Associate Scientist - Cellular Immune Assays

Pearl River, New York
May 14 2021
Position Type
Full Time
Organization Type
Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.

As a Pfizer colleague you will be at the center of our operations and you'll find that everything we do, every day, is in line with an unwavering commitment to quality. Your skills and expertise will ensure that all work is to be done in a compliant manner.Your significant experience of applying knowledge of principles, concepts, and practices of the discipline will make you a critical member of the team. It is your hard work and focus that will help in making Pfizer ready to achieve new milestones and help patients across the globe.

Role Summary

This is a laboratory-based position within the Vaccine Research and Development - Clinical and Diagnostic Assay Development. The primary responsibility is to support development and testing of novel adjuvant formulations. Senior Associate Scientist will be responsible for testing samples from cell cultures and tissue samples from animal studies. Later, candidate's responsibilities will be extended to early stage (Phase I) clinical studies. The role is focused on various cell-based immunoassays including but not limited to intra-cellular staining, flow cytometry, sell sorting, ELISPOT. This position requires assisting with humoral immune assays, molecular and virology work. Candidate will also be responsible for maintenance and upkeep of equipment required for these assays. The role requires basic knowledge of cellular assays and experience of working in a BSL2 levellaboratory under aseptic condition. Candidate with good analytical skills needs attention to detail and the ability to clearly document and present complex biological data. Candidate is required to multitask and collaborate with team members that is required to meet business-critical deadlines. A ll work is to be done in a compliant manner according to relevant Standard Operating Procedure (SOP) and Good Lab Practices (cGLP) guidelines.

  • Conduct various cell-based assays (flow cytometry, cell sorting, ELISPOT) in accordance with BSL2 laboratory requirements.
  • Perform sample preparation for preclinical and clinical serology in functional assays to support vaccine development and clinical studies.
  • Document experiments, analyze data, provide interpretation and conclusions obtained from experiments.
  • Record experimental data contemporaneously in an electronic notebook.
  • Contribute to drafting experimental protocols and technical reports.
  • Identify and report any experimental problems, proactively troubleshoot causative factors, and implement necessary corrections following discussion with supervisor.
  • Support the efficient and compliant operation of the laboratory by developing appropriate processes and standard operating procedures, working with others to operate the laboratory, and by becoming an expert user in key areas of operation (such as LIMS and GDMS).
  • Assist in the sourcing and maintenance of reagents required to conduct clinical flow cytometry assays in a compliant manner.
  • Maintain and build a broad knowledge of key assay platforms and the scientific rationale supporting the assays through appropriate training and self-learning.
  • Assist withqualifications/validations of new instruments and custom methods.
  • Contribute to achievement of immediate work group goals and collaborate with other team members.
  • Satisfactorily completes all cGLP (current Good Laboratory Practices) and safety training in conformance with requirements.
  • Interact with external vendors to obtain quotes, and purchase reagents.


Basic qualifications
  • Bachelor's Degree in Biology, Biotechnology, Microbiology, Immunology, Life Sciences or related discipline.
  • 2+ years of experience in cell culture and cell based assays ( or MS in related discipline with 1+ year of experience).
  • Experience in working in a tissue culture laboratory with samples requiring BSL2 containment.
  • Experience in working with animal and/or human samples.
  • Experienced in conducting cellular immunoassays (flow cytometry, cell sorting, ELISPOT).
  • Ability to perform analysis of data.
  • Experience with experimental design and the interpretation of results.
  • Effective verbal and written communication skills.
  • Proficiency with personal computers, including word processing, Excel, PowerPoint and relevant scientific software.
  • Good interpersonal, organizational and documentation skills.
  • Strong communication skills and ability to work across a matrix team.
  • The position has physical requirements of basic office and laboratory work (sitting, standing, and walking).
  • The mental requirements include the ability to analyze data, design experiments, and present complex concepts to colleagues.

  • Basic laboratory skills in the area of quantitative-PCR, molecular biology, western blotting.
  • Experience of working in an industrial laboratory with a defined quality system.
  • Experience of working in a cGLP-compliant environment.
  • Experience in the implementation and use of laboratory information management systems (e.g. LIMS).

Other Job Details:
  • Last Date to Apply for Job: May 21, 2021
  • Eligible for Employee Referral Bonus: YES


Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development