Associate Scientist, Assay Development & External Lab Management

Why Patients Need You

Pfizer's purpose is to deliver breakthroughs that change patients' lives. Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies and vaccines that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best in class medicines to patients around the world.

What You Will Achieve

As an Associate Scientist, you will be at the center of our operations and you'll find that everything we do, every day, is in line with an unwavering commitment to quality. You will have the important role to generate high-quality immunoassay data in a regulated Good Laboratory Practices (GLP) setting to support Pfizer's vaccine programs according to Standard Operating Procedures. You will be involved in managing and supporting external Peripheral Blood Mononuclear Cells (PBMC) laboratories and internal assay development in the Immune Phenotyping Group. The candidate will be responsible for maintenance and upkeep of equipment required for these assays and must maintain reagent and freezer inventory. Experience of working in a BSL2 level tissue culture laboratory is required, as well as an understanding of cellular immunology and the key assay platforms of flow cytometry and ELISPOT. The role requires good analytical skills, attention to detail and the ability to clearly document and present complex biological data. Incumbent is required to multitask and work as part of a team that is required to meet business-critical deadlines.

Your strong foundation in general scientific practice, its principles and concepts will help in meeting critical deadlines. You will be relied on as a technical contributor to assess the assigned tasks and make decisions that involve direct application of your knowledge.

It is your hard work and focus that will make Pfizer ready to achieve new milestones and help patients across the globe.

How You Will Achieve It

• Exercise and build basic team effectiveness skills {e.g., commitment, feedback, consensus management} within the immediate work group and external lab partnerships
• Perform job responsibilities in compliance with current Good Manufacturing Practices/ Good Laboratory Practice (cGMP/GLP) and all other regulatory agency requirements.
• Assist in updating and writing documents associated with Immune Phenotyping work including information/data archiving, Standard Operating Procedure and status reports.
• Perform isolation of Peripheral Blood Mononuclear Cells (PBMCs).
• Assist in ordering supplies, maintain inventory and ship reagents/supplies necessary for internal and external laboratories
• Monitor external PBMC processing labs throughout a clinical trial
• Cross train on clinical assays in accordance with Good Clinical Laboratory Practice (GCLP) requirements.
• Present progress on assay development and sample analysis to colleagues and senior management.
• Collect and analyze data on a per project basis to support troubleshooting, qualification and other lab projects.
• Provide critical data review of clinical and non-clinical data.
• Maintain and build a broad knowledge of key assay platforms (including flow cytometry and ELISPOT assays) and the scientific rationale underpinning the assays through appropriate training and self-learning.
• Stay current on all departmental and corporate training.

Qualifications

Must-Have

• Bachelor's Degree
• Excellent interpersonal skills and ability to interact with multiple external partners in a dynamic fashion.
• Experience in working with human samples.
• Experience working in a tissue culture laboratory with samples requiring BSL2 containment.
• Experienced in conducting ELISA or ELISPOT assays
• Strong attention to detail and ability to collaborate and work in team environment
• Good Computer skills including word processing, Excel, PowerPoint and relevant scientific software

Nice-to-Have

• Pharmaceutical and biotech drug experience
• PBMC isolation experience
• Clinical trial oversight and management
• Experience in assay development and troubleshooting
• Ability to travel up to 10% of the time

PHYSICAL/MENTAL REQUIREMENTS

Must be able to perform physical activities such as standing or sitting at the lab bench or biosafety cabinet.

NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS

Travel to external labs will include the requirement to adhere to each lab's specific safety regulations

- Last Date to Apply for Job: June 4th, 2021
- Eligible for Employee Referral Bonus: YES

Sunshine Act

Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.

EEO & Employment Eligibility

Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer.

Research and Development